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Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate

Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea
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Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Roman Dembinski
Molecules 2015, 20(8), 14022-14032; https://doi.org/10.3390/molecules200814022
Received: 7 July 2015 / Revised: 29 July 2015 / Accepted: 31 July 2015 / Published: 3 August 2015
(This article belongs to the Section Organic Chemistry)
3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity. View Full-Text
Keywords: 3-(Diarylmethylene)oxindole; one-pot reaction; aryl triflate; palladium-catalyzed reaction 3-(Diarylmethylene)oxindole; one-pot reaction; aryl triflate; palladium-catalyzed reaction
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MDPI and ACS Style

Lee, D.; Park, S.; Yu, Y.; Shin, K.J.; Seo, J.H. Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate. Molecules 2015, 20, 14022-14032. https://doi.org/10.3390/molecules200814022

AMA Style

Lee D, Park S, Yu Y, Shin KJ, Seo JH. Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate. Molecules. 2015; 20(8):14022-14032. https://doi.org/10.3390/molecules200814022

Chicago/Turabian Style

Lee, Dahye, Sunhwa Park, Yoseb Yu, Kye J. Shin, and Jae H. Seo 2015. "Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate" Molecules 20, no. 8: 14022-14032. https://doi.org/10.3390/molecules200814022

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