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Carapanolides T–X from Carapa guianensis (Andiroba) Seeds

Laboratory of Medicinal Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan
Laboratory of Pharmaceutical Organic Chemistry, Faculty of Pharmacy Kinki University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan
Author to whom correspondence should be addressed.
Academic Editor: Isabel C. F. R. Ferreira
Molecules 2015, 20(11), 20955-20966;
Received: 29 October 2015 / Revised: 16 November 2015 / Accepted: 16 November 2015 / Published: 24 November 2015
(This article belongs to the Section Natural Products Chemistry)
PDF [1764 KB, uploaded 24 November 2015]


Two new mexicanolide-type limonoids, carapanolides T–U (12), and three new phragmalin-type limonoids, carapanolides V–X (35), were isolated from the seeds of Carapa guianensis (andiroba). Their structures were determined on the basis of 1D- and 2D-NMR spectroscopy. View Full-Text
Keywords: Carapa guianensis; Meliaceae; andiroba; seeds; limonoid; mexicanolide; phragmalin; NO production Carapa guianensis; Meliaceae; andiroba; seeds; limonoid; mexicanolide; phragmalin; NO production

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Miyake, T.; Ishimoto, S.; Ishimatsu, N.; Higuchi, K.; Minoura, K.; Kikuchi, T.; Yamada, T.; Muraoka, O.; Tanaka, R. Carapanolides T–X from Carapa guianensis (Andiroba) Seeds. Molecules 2015, 20, 20955-20966.

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