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Molecules, Volume 19, Issue 7

July 2014 - 121 articles

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Articles (121)

  • Article
  • Open Access
38 Citations
7,999 Views
17 Pages

A Combinatorial Approach to Biophysically Characterise Chemokine-Glycan Binding Affinities for Drug Development

  • Tanja Gerlza,
  • Bianca Hecher,
  • Dalibor Jeremic,
  • Thomas Fuchs,
  • Martha Gschwandtner,
  • Angelika Falsone,
  • Bernd Gesslbauer and
  • Andreas J. Kungl

22 July 2014

Chemokine binding to glycosaminoglycans (GAGs) is recognised to be an important step in inflammation and other pathological disorders like tumor growth and metastasis. Although different ways and strategies to interfere with these interactions are be...

  • Article
  • Open Access
20 Citations
8,597 Views
15 Pages

Effects of Echium plantagineum L. Bee Pollen on Basophil Degranulation: Relationship with Metabolic Profile

  • Eduarda Moita,
  • Carla Sousa,
  • Paula B. Andrade,
  • Fátima Fernandes,
  • Brígida R. Pinho,
  • Luís R. Silva and
  • Patrícia Valentão

22 July 2014

This study aimed to evaluate the anti-allergic potential of Echium plantagineum L. bee pollen and to characterize its primary metabolites. The activity of E. plantagineum hydromethanolic extract, devoid of alkaloids, was tested against β-hexosaminida...

  • Review
  • Open Access
112 Citations
25,944 Views
20 Pages

22 July 2014

“Dragon’s blood” is the name given to a deep red resin obtained from a variety of plant sources. The resin extracted from stems of Dracaena cochinchinensis is one such source of “dragon’s blood”. It has a reputation for facilitating blood circulation...

  • Article
  • Open Access
15 Citations
6,919 Views
13 Pages

Nonlinear Optical Molecular Switches for Alkali Ion Identification

  • Aurélie Plaquet,
  • Benoît Champagne and
  • Frédéric Castet

21 July 2014

This work demonstrates by means of DFT and ab initio calculations that recognition of alkali cations can be achieved by probing the variations of the second-order nonlinear optical properties along the commutation process in spiropyran/merocyanine sy...

  • Article
  • Open Access
49 Citations
15,804 Views
14 Pages

MALDI Mass Spectrometry Imaging for the Simultaneous Location of Resveratrol, Pterostilbene and Viniferins on Grapevine Leaves

  • Loïc Becker,
  • Vincent Carré,
  • Anne Poutaraud,
  • Didier Merdinoglu and
  • Patrick Chaimbault

21 July 2014

To investigate the in-situ response to a stress, grapevine leaves have been subjected to mass spectrometry imaging (MSI) experiments. The Matrix Assisted Laser Desorption/Ionisation (MALDI) approach using different matrices has been evaluated. Among...

  • Article
  • Open Access
14 Citations
7,952 Views
17 Pages

Saponins of Trifolium spp. Aerial Parts as Modulators of Candida Albicans Virulence Attributes

  • Aleksandra Budzyńska,
  • Beata Sadowska,
  • Marzena Więckowska-Szakiel,
  • Bartłomiej Micota,
  • Anna Stochmal,
  • Dariusz Jędrejek,
  • Łukasz Pecio and
  • Barbara Różalska

21 July 2014

The aim was to provide the insight into the biology of C. albicans influenced by undescribed yet properties of saponin-rich (80%–98%) fractions (SAPFs), isolated from extracts of Trifolium alexandrinum, T. incarnatum, T. resupinatum var. resupinatum...

  • Article
  • Open Access
30 Citations
8,162 Views
7 Pages

Two New Iridoids from Verbena officinalis L.

  • Jicheng Shu,
  • Guixin Chou and
  • Zhengtao Wang

18 July 2014

Two new iridoids, 3-(5-(methoxycarbonyl)-2-oxo-2H-pyran-3-yl)butanoic acid, named verbeofflin I (1), and 7-hydroxydehydrohastatoside (2), were isolated from the aerial part of Verbena officinalis L, along with three known iridoids, verbenalin (3), 3...

  • Article
  • Open Access
100 Citations
13,895 Views
15 Pages

Antioxidant, Antimicrobial and Phytochemical Variations in Thirteen Moringa oleifera Lam. Cultivars

  • Ashwell R. Ndhlala,
  • Rofhiwa Mulaudzi,
  • Bhekumthetho Ncube,
  • Hafiz A. Abdelgadir,
  • Christian P. Du Plooy and
  • Johannes Van Staden

18 July 2014

A study was undertaken to assess variation in antioxidant, antimicrobial and phytochemical properties of thirteen Moringa oleifera cultivars obtained from different locations across the globe. Standard antioxidant methods including the DPPH scavengin...

  • Article
  • Open Access
26 Citations
11,884 Views
29 Pages

Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles

  • Sónia Pérez-Rentero,
  • Santiago Grijalvo,
  • Guillem Peñuelas,
  • Carme Fàbrega and
  • Ramon Eritja

18 July 2014

Oligonucleotide gold nanoparticle conjugates are being used as diagnostic tools and gene silencing experiments. Thiol-chemistry is mostly used to functionalize gold nanoparticles with oligonucleotides and to incorporate DNA or RNA molecules onto gold...

  • Review
  • Open Access
17 Citations
13,592 Views
10 Pages

18 July 2014

In the U.S., there has been a recent surge in Korean black raspberry products available and in the number of reports about this species appearing in the scientific literature. Despite this, the majority of products sold and the work carried out has b...

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Molecules - ISSN 1420-3049