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Volume 16
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10.3390/molecules16043119
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Open AccessArticle

Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia

by
Syazreen Nadia Sulaiman
1,
Mat Ropi Mukhtar
1,*,
A Hamid A Hadi
1,
Khalijah Awang
1,
Hazrina Hazni
1,
Azeana Zahari
1,
Marc Litaudon
2,
Kazumasa Zaima
3 and
Hiroshi Morita
3
1
Centre for Natural Products and Drug Discovery, Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
2
Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS, 1, Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France
3
Faculty of Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan
*
Author to whom correspondence should be addressed.
Molecules 2011, 16(4), 3119-3127; https://doi.org/10.3390/molecules16043119
Received: 7 January 2011 / Revised: 5 April 2011 / Accepted: 11 April 2011 / Published: 13 April 2011
(This article belongs to the Section Natural Products Chemistry)
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Abstract

A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, complete 13C-NMR data of N-allyl-laurolitsine (2) was also reported. The alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data. N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta. View Full-Text
Keywords: bisbenzylisoquinoline; lancifoliaine; N-allyllaurolitsine; Lauraceae; vaso-relaxant activity bisbenzylisoquinoline; lancifoliaine; N-allyllaurolitsine; Lauraceae; vaso-relaxant activity
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MDPI and ACS Style

Sulaiman, S.N.; Mukhtar, M.R.; Hadi, A H.A; Awang, K.; Hazni, H.; Zahari, A.; Litaudon, M.; Zaima, K.; Morita, H. Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia. Molecules 2011, 16, 3119-3127. https://doi.org/10.3390/molecules16043119

AMA Style

Sulaiman SN, Mukhtar MR, Hadi AHA, Awang K, Hazni H, Zahari A, Litaudon M, Zaima K, Morita H. Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia. Molecules. 2011; 16(4):3119-3127. https://doi.org/10.3390/molecules16043119

Chicago/Turabian Style

Sulaiman, Syazreen Nadia; Mukhtar, Mat Ropi; Hadi, A Hamid A; Awang, Khalijah; Hazni, Hazrina; Zahari, Azeana; Litaudon, Marc; Zaima, Kazumasa; Morita, Hiroshi. 2011. "Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia" Molecules 16, no. 4: 3119-3127. https://doi.org/10.3390/molecules16043119

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