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Molecules, Volume 16, Issue 3

March 2011 - 57 articles

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Articles (57)

  • Article
  • Open Access
16 Citations
13,157 Views
22 Pages

Purification, Biochemical Characterization, and Bioactive Properties of a Lectin Purified from the Seeds of White Tepary Bean (Phaseolus Acutifolius Variety Latifolius)

  • Carmen Valadez-Vega,
  • Ana María Guzmán-Partida,
  • Francisco Javier Soto-Cordova,
  • Gerardo Álvarez-Manilla,
  • José A. Morales-González,
  • Eduardo Madrigal-Santillán,
  • José Roberto Villagómez-Ibarra,
  • Clara Zúñiga-Pérez,
  • José Gutiérrez-Salinas and
  • Marco A. Becerril-Flores

21 March 2011

The present work shows the characterization of Phaseolus acutifolius variety latifolius, on which little research has been published, and provides detailed information on the corresponding lectin. This protein was purified from a semi-domesticated li...

  • Article
  • Open Access
69 Citations
17,883 Views
16 Pages

Panduratin A Inhibits the Growth of A549 Cells through Induction of Apoptosis and Inhibition of NF-KappaB Translocation

  • Shiau-Chuen Cheah,
  • David R. Appleton,
  • Sui-Ting Lee,
  • May-Lynn Lam,
  • A. Hamid A. Hadi and
  • Mohd. Rais Mustafa

21 March 2011

In the present study we investigated the effects of panduratin A, isolated from Boesenbergia rotunda, on proliferation and apoptosis in A549 human non-small cell lung cancer cells. Cell proliferation and induction of apoptosis was determined by the r...

  • Communication
  • Open Access
22 Citations
8,596 Views
10 Pages

LC/MS Guided Isolation of Alkaloids from Lotus Leaves by pH-Zone-Refining Counter-Current Chromatography

  • Xia Xu,
  • Cui-Rong Sun,
  • Xiao-Jing Dai,
  • Rui-Lin Hu,
  • Yuan-Jiang Pan and
  • Zhang-Fa Yang

18 March 2011

The traditional methods used in natural product separation primarily target the major components and the minor components may thus be lost during the separation procedure. Consequently, it’s necessary to develop efficient methods for the preparative...

  • Article
  • Open Access
17 Citations
8,829 Views
8 Pages

Synthesis and Biological Evaluation of Novel Acenaphthene Derivatives as Potential Antitumor Agents

  • Yong-Mei Xie,
  • Yi Deng,
  • Xiao-Yun Dai,
  • Jie Liu,
  • Liang Ouyang,
  • Yu-Quan Wei and
  • Ying-Lan Zhao

17 March 2011

Twelve novel acenaphthene derivatives have been synthesized. The structures of all compounds were confirmed by 1H-NMR, MS and elemental analysis. Their antitumor activities were evaluated in six human solid tumor cell lines, namely non-small cell lun...

  • Article
  • Open Access
18 Citations
9,872 Views
15 Pages

Antioxidant Bibenzyl Derivatives from Notholaena nivea Desv.

  • Giuseppina Cioffi,
  • Paola Montoro,
  • Olga Lock De Ugaz,
  • Antonio Vassallo,
  • Lorella Severino,
  • Cosimo Pizza and
  • Nunziatina De Tommasi

17 March 2011

Four new bibenzyl derivatives were isolated, together with other known bibenzyls, by bioassay-guided fractionation of a CHCl3-MeOH extract of Notholaena nivea Desv. (Pteridaceae) aerial parts. The structures were elucidated by NMR, ESIMS and other sp...

  • Article
  • Open Access
119 Citations
10,052 Views
9 Pages

17 March 2011

The aim of this study was to investigate the effects of Lycium barbarum Polysaccharide (LBP) on alcohol-induced liver damage in rats. A total of 36 rats were divided into control, ethanol and ethanol + LBP groups. Rats in the ethanol group were fed 7...

  • Article
  • Open Access
42 Citations
9,203 Views
12 Pages

16 March 2011

Headspace solid-phase microextraction (HS-SPME; PDMS/DVB fibre) and ultrasonic solvent extraction (USE; solvent A: pentane and diethyl ether (1:2 v/v), solvent B: dichloromethane) followed by gas chromatography and mass spectrometry (GC, GC-MS) were...

  • Article
  • Open Access
39 Citations
12,375 Views
15 Pages

Role of the Morphology and Polyphosphate in Trichoderma harzianum Related to Cadmium Removal

  • Adriana De Freitas Lima,
  • Gabrielle Ferreira de Moura,
  • Marcos Antonio Barbosa de Lima,
  • Patrícia Mendes de Souza,
  • Carlos Alberto Alves da Silva,
  • Galba Maria De Campos Takaki and
  • Aline Elesbão Do Nascimento

15 March 2011

This study concerns the metabolism of polyphosphate in Trichoderma harzianum, a biocontrol agent with innate resistance against most chemicals used in agriculture, including metals, when grown in the presence of different concentrations of cadmium. T...

  • Article
  • Open Access
14 Citations
8,850 Views
6 Pages

Fungicidal Properties of the Essential Oil of Hesperozygis marifolia on Aspergillus flavus Link

  • Marco Martín González-Chávez,
  • Norma Cecilia Cárdenas-Ortega,
  • Cristina Andrea Méndez-Ramos and
  • Salud Pérez-Gutiérrez

15 March 2011

The chemical composition of the essential oil from Hesperozygis marifolia was analyzed by gas chromatography-mass spectrometry (GC-MS), and fourteen compounds were identified. (R)-pulegone (40.75%), isomenthone (30.34%) and menthone (4.46%) were foun...

  • Review
  • Open Access
51 Citations
13,816 Views
23 Pages

Quantitative Mass Spectrometry for Bacterial Protein Toxins — A Sensitive, Specific, High-Throughput Tool for Detection and Diagnosis

  • Anne E. Boyer,
  • Maribel Gallegos-Candela,
  • Renato C. Lins,
  • Zsuzsanna Kuklenyik,
  • Adrian Woolfitt,
  • Hercules Moura,
  • Suzanne Kalb,
  • Conrad P. Quinn and
  • John R. Barr

14 March 2011

Matrix-assisted laser-desorption time-of-flight (MALDI-TOF) mass spectrometry (MS) is a valuable high-throughput tool for peptide analysis. Liquid chromatography electrospray ionization (LC-ESI) tandem-MS provides sensitive and specific quantificatio...

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Molecules - ISSN 1420-3049