Synthesis of β-Maltooligosaccharides of Glycitein and Daidzein and their Anti-Oxidant and Anti-Allergic Activities
1
Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan
2
Department of Life Science, Okayama University of Science, 1-1 Ridai-cho, Kita-ku, Okayama 700-0005, Japan
*
Authors to whom correspondence should be addressed.
Molecules 2010, 15(8), 5153-5161; https://doi.org/10.3390/molecules15085153
Received: 10 June 2010 / Revised: 25 July 2010 / Accepted: 27 July 2010 / Published: 29 July 2010
(This article belongs to the Special Issue Antioxidants)
The production of β-maltooligosaccharides of glycitein and daidzein using Lactobacillus delbrueckii and cyclodextrin glucanotransferase (CGTase) as biocatalysts was investigated. The cells of L. delbrueckii glucosylated glycitein and daidzein to give their corresponding 4'- and 7-O-β-glucosides. The β-glucosides of glycitein and daidzein were converted into the corresponding β-maltooligosides by CGTase. The 7-O-β-glucosides of glycitein and daidzein and 7-O-β-maltoside of glycitein showed inhibitory effects on IgE antibody production. On the other hand, β-glucosides of glycitein and daidzein exerted 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity and supeoxide-radical scavenging activity.
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Keywords:
glycitein; daidzein; β-maltooligosaccharides; anti-allergic activity; anti-oxidant activity
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MDPI and ACS Style
Shimoda, K.; Hamada, H. Synthesis of β-Maltooligosaccharides of Glycitein and Daidzein and their Anti-Oxidant and Anti-Allergic Activities. Molecules 2010, 15, 5153-5161.
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