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Molecules, Volume 15, Issue 7

July 2010 - 36 articles

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Articles (36)

  • Article
  • Open Access
14 Citations
8,537 Views
14 Pages

23 July 2010

The quality of diverse compound selection mainly depends on cluster algorithms, descriptors, the combinations of the descriptors, and similarity metrics. The Jarvis-Patrick algorithm, MDL search keys, and Daylight fingerprints are a well accepted alg...

  • Article
  • Open Access
3 Citations
7,977 Views
8 Pages

23 July 2010

We have developed a Pt(COD)Cl2-catalyzed hydrative cyclization of 1,6-diynes leading to the formation of functionalized cyclohexenones in good yields.

  • Article
  • Open Access
23 Citations
9,633 Views
13 Pages

23 July 2010

Unmanaged sudden withdrawal from the excessive consumption of alcohol (ethanol) adversely alters neuronal integrity in vulnerable brain regions such as the cerebellum, hippocampus, or cortex. In addition to well known hyperexcitatory neurotransmissio...

  • Article
  • Open Access
19 Citations
10,459 Views
19 Pages

Anethole Isomerization and Dimerization Induced by Acid Sites or UV Irradiation

  • Hans T. Castro,
  • Jairo René Martínez and
  • Elena Stashenko

22 July 2010

The formation of cis-anethole and various dimers as a result of the exposure of trans-anethole to microporous solid acids (dealuminated HY zeolites), or UV-Vis irradiation was established by means of high resolution gas chromatography coupled to mass...

  • Review
  • Open Access
35 Citations
11,344 Views
14 Pages

20 July 2010

This article is an account of the work carried out in the authors’ laboratory illustrating the usefulness of dendrimer design for nanoparticle palladium catalysis. The “click” synthesis of dendrimers constructed generation by generation by 1à3 C conn...

  • Article
  • Open Access
5 Citations
10,094 Views
23 Pages

Solid-Phase Synthetic Route to Multiple Derivatives of a Fundamental Peptide Unit

  • William L. Scott,
  • Ziniu Zhou,
  • Paweł Zajdel,
  • Maciej Pawłowski and
  • Martin J. O’Donnell

20 July 2010

Amino acids are Nature’s combinatorial building blocks. When substituted on both the amino and carboxyl sides they become the basic scaffold present in all peptides and proteins. We report a solid-phase synthetic route to large combinatorial variatio...

  • Review
  • Open Access
39 Citations
15,253 Views
28 Pages

20 July 2010

Unmanaged sudden withdrawal from the excessive consumption of alcohol (ethanol) adversely alters neuronal integrity in vulnerable brain regions such as the cerebellum, hippocampus, or cortex. In addition to well known hyperexcitatory neurotransmissio...

  • Article
  • Open Access
43 Citations
10,102 Views
13 Pages

16 July 2010

The antioxidant activities of the various extracts and fractions from the herbs of Artemisia selegensis Turcz (AST) were investigated by in vitro and in vivo assays. FRAP, DPPH and ABTS assays were used to evaluate the antioxidant activities of the e...

  • Article
  • Open Access
3 Citations
10,396 Views
10 Pages

Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers

  • Mª Jesús Pérez De Vega,
  • Mª Teresa García-López,
  • Laura Zaccaro,
  • Miriam Royo,
  • Fernando Albericio,
  • Asia Fernández-Carvajal,
  • Antonio Ferrer-Montiel and
  • Rosario González-Muñiz

15 July 2010

Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N–terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.

  • Article
  • Open Access
25 Citations
11,520 Views
16 Pages

14 July 2010

With the aim of developing new molecular devices having higher photo-hydrogen-evolving activity, Pt(ppy)ClX units (ppy = 2-phenylpyridinate, X = Cl- or DMSO; DMSO = dimethylsulfoxide) have been employed as an H2-evolving site, as the catalytic activi...

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Molecules - ISSN 1420-3049