Special Issue "Enzyme Immobilization"

Quicklinks

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Molecular Diversity".

Deadline for manuscript submissions: closed (15 May 2014)

Special Issue Editor

Guest Editor
Prof. Dr. Roberto Fernandez-Lafuente
Institute of catalysis and petrochemsitry-CSIC, Campus UAM-CSIC Cantoblanco, 28049 Madrid, Spain
Website: http://www.icp.csic.es/grupo-de-investigacion.php?id=24
E-Mail: rfl@icp.csic.es
Phone: + 34 91 585 4941
Fax: +34 91 585 4760
Interests: enzyme immobilization; stabilization and purification; biocatalyst and biosensors design; bioprocesses optimization

Special Issue Information

Dear Collegues,

The immobilization of enzymes and proteins is a seemingly ancient research area that still attracts great interest. The initial interest in enzyme immobilization was motivated by a desire to simplify the reuse of these expensive biocatalysts. However, at present, immobilization has developed into a very powerful tool that has been used to overcome many enzyme limitations. Applications include improving enzyme stability, activity, selectivity or specificity, reducing inhibition problems, and even coupling immobilization and purification, etc.

To date, many immobilization protocols have been reported. However, research is still the cornerstone of obtaining full control of the orientation of the enzyme on the support surface, and of the intensity of the support-enzyme interactions. Moreover, immobilization should not be considered an alternative to any other enzyme improvement strategy. For example, genetic and chemical tools may be utilized to produce a better enzyme that maintain improved properties after immobilization, or to improve immobilization; in both situations, alternative techniques produce an improved biocatalyst.

Thus, the efforts to design strategies involving the coupled use of immobilization with microbiological (e.g., the use of thermophilic enzymes), chemical or genetic modifications are of special interest. Enzymes are co-immobilized to catalyze cascade reactions; however, this process may produce additional complications. This special issue invites submissions (i.e., research or review papers) discussing the design of new immobilization protocols, especially when the control of the enzyme orientation is intended by design of the support, or modification of the enzyme. Papers related to the modification of immobilized enzymes, or to the modification of the support surface after enzyme immobilization, are also welcome.

Dr. Roberto Fernandez-Lafuente
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


Keywords

  • controlled enzyme immobilization and co-immobilization
  • heterofunctional supports
  • improved enzyme properties via immobilization
  • chemical or genetic modification and immobilization
  • immobilization of enzymes from thermophilic microorganisms

Published Papers (24 papers)

Download All Papers
Sort by:
Display options:
Select articles Export citation of selected articles as:
Select/unselect all
Displaying article 1-24
p. 20671-20674
by
Molecules 2014, 19(12), 20671-20674; doi:10.3390/molecules191220671
Received: 5 December 2014; Accepted: 8 December 2014 / Published: 10 December 2014
Show/Hide Abstract | PDF Full-text (645 KB)
(This article belongs to the Special Issue Enzyme Immobilization)
p. 19390-19406
by  and
Molecules 2014, 19(12), 19390-19406; doi:10.3390/molecules191219390
Received: 31 July 2014; in revised form: 15 November 2014 / Accepted: 17 November 2014 / Published: 25 November 2014
Show/Hide Abstract | PDF Full-text (2491 KB)
(This article belongs to the Special Issue Enzyme Immobilization)
p. 16794-16809
by , , , , ,  and
Molecules 2014, 19(10), 16794-16809; doi:10.3390/molecules191016794
Received: 16 May 2014; in revised form: 22 September 2014 / Accepted: 8 October 2014 / Published: 17 October 2014
Show/Hide Abstract | PDF Full-text (389 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 15768-15782
by  and
Molecules 2014, 19(10), 15768-15782; doi:10.3390/molecules191015768
Received: 14 May 2014; in revised form: 9 August 2014 / Accepted: 7 September 2014 / Published: 29 September 2014
Show/Hide Abstract | PDF Full-text (1766 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 14615-14624
by , , , , ,  and
Molecules 2014, 19(9), 14615-14624; doi:10.3390/molecules190914615
Received: 16 May 2014; in revised form: 16 August 2014 / Accepted: 22 August 2014 / Published: 15 September 2014
Show/Hide Abstract | PDF Full-text (731 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 14139-14194
by  and
Molecules 2014, 19(9), 14139-14194; doi:10.3390/molecules190914139
Received: 5 July 2014; in revised form: 9 August 2014 / Accepted: 22 August 2014 / Published: 9 September 2014
Show/Hide Abstract | PDF Full-text (1733 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 12461-12485
by , , , , ,  and
Molecules 2014, 19(8), 12461-12485; doi:10.3390/molecules190812461
Received: 28 May 2014; in revised form: 2 August 2014 / Accepted: 5 August 2014 / Published: 18 August 2014
Show/Hide Abstract | PDF Full-text (1143 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 12509-12530
by ,  and
Molecules 2014, 19(8), 12509-12530; doi:10.3390/molecules190812509
Received: 19 May 2014; in revised form: 28 July 2014 / Accepted: 1 August 2014 / Published: 18 August 2014
Show/Hide Abstract | PDF Full-text (1146 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 11419-11439
by , , , , , ,  and
Molecules 2014, 19(8), 11419-11439; doi:10.3390/molecules190811419
Received: 5 May 2014; in revised form: 22 July 2014 / Accepted: 22 July 2014 / Published: 4 August 2014
Show/Hide Abstract | PDF Full-text (1249 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 11465-11486
by , , , ,  and
Molecules 2014, 19(8), 11465-11486; doi:10.3390/molecules190811465
Received: 23 May 2014; in revised form: 9 July 2014 / Accepted: 9 July 2014 / Published: 4 August 2014
Show/Hide Abstract | PDF Full-text (1045 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 11231-11249
by , , , , ,  and
Molecules 2014, 19(8), 11231-11249; doi:10.3390/molecules190811231
Received: 11 June 2014; in revised form: 23 July 2014 / Accepted: 24 July 2014 / Published: 31 July 2014
Show/Hide Abstract | PDF Full-text (936 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 9818-9837
by ,  and
Molecules 2014, 19(7), 9818-9837; doi:10.3390/molecules19079818
Received: 16 May 2014; in revised form: 23 June 2014 / Accepted: 2 July 2014 / Published: 8 July 2014
Show/Hide Abstract | PDF Full-text (517 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 9838-9849
by , , , , , ,  and
Molecules 2014, 19(7), 9838-9849; doi:10.3390/molecules19079838
Received: 21 May 2014; in revised form: 3 July 2014 / Accepted: 4 July 2014 / Published: 8 July 2014
Show/Hide Abstract | PDF Full-text (330 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 9850-9863
by , , ,  and
Molecules 2014, 19(7), 9850-9863; doi:10.3390/molecules19079850
Received: 19 May 2014; in revised form: 23 June 2014 / Accepted: 24 June 2014 / Published: 8 July 2014
Show/Hide Abstract | PDF Full-text (490 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 9562-9576
by , , , , , ,  and
Molecules 2014, 19(7), 9562-9576; doi:10.3390/molecules19079562
Received: 26 May 2014; in revised form: 30 June 2014 / Accepted: 1 July 2014 / Published: 7 July 2014
Show/Hide Abstract | PDF Full-text (457 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 8995-9018
by ,  and
Molecules 2014, 19(7), 8995-9018; doi:10.3390/molecules19078995
Received: 12 May 2014; in revised form: 13 June 2014 / Accepted: 16 June 2014 / Published: 27 June 2014
Show/Hide Abstract | Cited by 1 | PDF Full-text (858 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 8610-8628
by ,  and
Molecules 2014, 19(6), 8610-8628; doi:10.3390/molecules19068610
Received: 4 May 2014; in revised form: 20 June 2014 / Accepted: 20 June 2014 / Published: 24 June 2014
Show/Hide Abstract | PDF Full-text (565 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 8629-8643
by , ,  and
Molecules 2014, 19(6), 8629-8643; doi:10.3390/molecules19068629
Received: 16 May 2014; in revised form: 19 June 2014 / Accepted: 19 June 2014 / Published: 24 June 2014
Show/Hide Abstract | PDF Full-text (279 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 8027-8038
by , ,  and
Molecules 2014, 19(6), 8027-8038; doi:10.3390/molecules19068027
Received: 8 March 2014; in revised form: 4 June 2014 / Accepted: 6 June 2014 / Published: 13 June 2014
Show/Hide Abstract | PDF Full-text (541 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 7629-7645
by , , , ,  and
Molecules 2014, 19(6), 7629-7645; doi:10.3390/molecules19067629
Received: 3 April 2014; in revised form: 3 June 2014 / Accepted: 4 June 2014 / Published: 10 June 2014
Show/Hide Abstract | PDF Full-text (240 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 7341-7355
by ,  and
Molecules 2014, 19(6), 7341-7355; doi:10.3390/molecules19067341
Received: 17 March 2014; in revised form: 30 May 2014 / Accepted: 3 June 2014 / Published: 5 June 2014
Show/Hide Abstract | PDF Full-text (651 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
p. 7057-7071
by , ,  and
Molecules 2014, 19(6), 7057-7071; doi:10.3390/molecules19067057
Received: 8 May 2014; in revised form: 20 May 2014 / Accepted: 23 May 2014 / Published: 30 May 2014
Show/Hide Abstract | Cited by 2 | PDF Full-text (1170 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
abstract graphic
p. 4997-5012
by , , , ,  and
Molecules 2014, 19(4), 4997-5012; doi:10.3390/molecules19044997
Received: 11 March 2014; in revised form: 15 April 2014 / Accepted: 17 April 2014 / Published: 22 April 2014
Show/Hide Abstract | PDF Full-text (2201 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Enzyme Immobilization)
p. 3376-3388
by , , , , ,  and
Molecules 2014, 19(3), 3376-3388; doi:10.3390/molecules19033376
Received: 20 January 2014; in revised form: 6 March 2014 / Accepted: 6 March 2014 / Published: 19 March 2014
Show/Hide Abstract | Cited by 1 | PDF Full-text (1930 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzyme Immobilization)
Select/unselect all
Displaying article 1-24
Select articles Export citation of selected articles as:

Last update: 18 July 2014

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert