Special Issue "Enzyme Immobilization 2016"
Deadline for manuscript submissions: closed (1 December 2016)
Prof. Dr. Roberto Fernandez-Lafuente
After the success of the first Special Issue edited by Molecules in 2014, I am very happy to announce the launching of a second issue on this topic. The immobilization of enzymes and proteins is a seemingly ancient research area that still attracts great interest. The initial interest in enzyme immobilization was motivated by a desire to simplify the reuse of these expensive biocatalysts. Nowadays, the research in this area has focused in its application to overcome many enzyme limitations, for example improving enzyme stability, activity, selectivity or specificity, reducing inhibition problems, and even coupling immobilization and purification.
Two years after the publication of the first issue in May 2014, where many interesting immobilization protocols were reported, still the control of the orientation of the enzyme on the support surface and of the intensity of the support-enzyme interactions is not properly solved. Coupling of genetic and chemical tools has been utilized to produce enzymes that may be better immobilized on tailor made supports. Each day more researches couple immobilization to any other strategy for enzyme stabilization and enhancement of their properties.
Thus, the efforts to design strategies involving the coupled use of immobilization with microbiological (e.g., the use of thermophilic enzymes), chemical or genetic modifications are of special interest. Enzymes are co-immobilized to catalyze cascade reactions; however, this process may produce additional complications, no always co-immobilization will be recommended. This Special Issue invites submissions (i.e., research or review papers) discussing the design of new immobilization protocols, especially when the control of the enzyme orientation is intended by design of the support, or modification of the enzyme. The use of the immobilized enzymes to take advantage of the catalytic improved properties will be also suitable for this second special issue. Papers related to the modification of immobilized enzymes, or to the modification of the support surface after enzyme immobilization, are also welcome.
Dr. Roberto Fernandez-Lafuente
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- controlled enzyme immobilization and co-immobilization
- heterofunctional supports
- improved enzyme properties via immobilization
- chemical or genetic modification and immobilization
- immobilization of enzymes from thermophilic microorganisms