Oxidative Stress and Inflammation, 3rd Edition

Dear Colleagues,

Oxidative stress is viewed as an imbalance between the production of reactive oxygen species (ROS) and their elimination by protective mechanisms, which can lead to chronic inflammation. Certain lifestyles and the intake of external unhealthy chemicals are the major causes of age-related chronic diseases and cancer. Their study includes disease pathology pathways, lifestyle, treatment, protection, and prevention of oxidative stress and inflammation. ROS are normally produced within the body in limited amounts and are essential compounds involved in the regulation of processes that can maintain cell homeostasis and functions (signal transduction, gene expression, and activation of receptors). An imbalance may cause oxidative stress, which can lead to lipid peroxidation, gene mutation, inflammation, and other complications. The harmful oxidative activity of ROS can be only counteracted by antioxidant/anti-inflammatory compounds, which may be both synthetic and natural, but are often characterized by several stability issues, such as poor water solubility and low bioavailability, which compromise their in vivo activities. The aim of this Topic is to collect research papers providing an overview of the current status of research on both natural and synthetic products with antioxidant properties that can counteract inflammatory diseases, including, but not necessarily restricted to, chemical compounds (synthetic or of natural origin), vitamins, peptides, micronutrients, non-starch polysaccharides, probiotics, postbiotics, prebiotics formulations containing functional foods, nutraceutical or cosmeceutical products, and innovative oral, systemic, or topical delivery methods that are capable of overcoming their stability issues.

Dr. Maria Letizia Manca
Dr. Amparo Nacher
Dr. Matteo Perra
Dr. Ines Castangia
Dr. Mohamad Allaw
Topic Editors