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Communication

10 Citations

21,133 Views

14 Pages

The Relationships between Intestinal Permeability and Target Antibodies for a Spectrum of Autoimmune Diseases

Datis Kharrazian,
Martha Herbert and
Jama Lambert

Int. J. Mol. Sci.2023, 24(22), 16352;https://doi.org/10.3390/ijms242216352

15 November 2023

The worldwide prevalence of autoimmune diseases that have limited treatment options and preventive strategies is rapidly rising. There is growing evidence that the microbiota and the integrity of the intestinal barrier play a role in autoimmune disea...

(This article belongs to the Special Issue Molecular Mechanisms of Gastrointestinal Immune System and Its Role in Gut Homeostasis and Pathologies)

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Article

15 Citations

9,075 Views

21 Pages

Correlation between Antibodies to Bacterial Lipopolysaccharides and Barrier Proteins in Sera Positive for ASCA and ANCA

Aristo Vojdani,
Elroy Vojdani,
Martha Herbert and
Datis Kharrazian

Int. J. Mol. Sci.2020, 21(4), 1381;https://doi.org/10.3390/ijms21041381

18 February 2020

Individuals with intestinal barrier dysfunction are more prone to autoimmunity. Lipopolysaccharides (LPS) from gut bacteria have been shown to play a role in systemic inflammation, leading to the opening of the gut and blood-brain barrier (BBB). This...

(This article belongs to the Special Issue Update on Basic and Molecular Research in Inflammatory Bowel Disease)

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