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7 Results Found

  • Review
  • Open Access
50 Citations
11,661 Views
34 Pages

Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review

  • Emanuela Martina,
  • Federico Diotallevi,
  • Giulia Radi,
  • Anna Campanati and
  • Annamaria Offidani

5 February 2021

Botulinum toxin is a superfamily of neurotoxins produced by the bacterium Clostridium Botulinum with well-established efficacy and safety profile in focal idiopathic hyperhidrosis. Recently, botulinum toxins have also been used in many other skin dis...

  • Review
  • Open Access
8 Citations
6,998 Views
13 Pages

It is understood that the skin is a peripheral lymphoid tissue that defends against external environmental stimuli. Continuous activation from these factors, on the other hand, promotes persistent inflammation at the local location and, occasionally,...

  • Review
  • Open Access
9 Citations
8,340 Views
19 Pages

Histologic Patterns and Clues to Autoinflammatory Diseases in Children: What a Cutaneous Biopsy Can Tell Us

  • Athanassios Kolivras,
  • Isabelle Meiers,
  • Ursula Sass and
  • Curtis T. Thompson

Autoinflammation is defined by aberrant, antigen-independent activation of the innate immune signaling pathways. This leads to increased, pro-inflammatory cytokine expression and subsequent inflammation. In contrast, autoimmune and allergic diseases...

  • Review
  • Open Access
36 Citations
13,138 Views
20 Pages

The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review

  • Federico Diotallevi,
  • Anna Campanati,
  • Emanuela Martina,
  • Giulia Radi,
  • Matteo Paolinelli,
  • Andrea Marani,
  • Elisa Molinelli,
  • Matteo Candelora,
  • Marina Taus and
  • Annamaria Offidani
  • + 2 authors

29 January 2022

Immune-mediated inflammatory skin diseases are characterized by a complex multifactorial etiology, in which genetic and environmental factors interact both in genesis and development of the disease. Nutrition is a complex and fascinating scenario, wh...

  • Systematic Review
  • Open Access
69 Citations
6,375 Views
17 Pages

The Burden of Hidradenitis Suppurativa Signs and Symptoms in Quality of Life: Systematic Review and Meta-Analysis

  • Trinidad Montero-Vilchez,
  • Pablo Diaz-Calvillo,
  • Juan-Angel Rodriguez-Pozo,
  • Carlos Cuenca-Barrales,
  • Antonio Martinez-Lopez,
  • Salvador Arias-Santiago and
  • Alejandro Molina-Leyva

Hidradenitis suppurativa (HS) is a chronic, recurrent and debilitating inflammatory skin disease of the hair follicle that usually presents as painful, deep-seated inflamed lesions in the apocrine gland-bearing areas of the body. HS patients suffer f...

  • Article
  • Open Access
20 Citations
3,187 Views
14 Pages

Little is known about the impact of hidradenitis suppurativa (HS) on patients’ sexuality. The aim of this research is to investigate the impact of HS on several previously unexplored aspects of sexuality. In March 2018, we conducted a crowd-sou...

  • Article
  • Open Access
2 Citations
1,751 Views
10 Pages

Retinal Microvascular Alterations in Hidradenitis Suppurativa Patients: A Pilot Study Using Optical Coherence Tomography Angiography

  • Marco Manfredini,
  • Emanuele Ragusa,
  • Matteo Gibertini,
  • Laura Bigi,
  • Barbara Ferrari,
  • Claudia Lasagni,
  • Cristina Magnoni,
  • Andrea Lazzerini,
  • Francesca Farnetani and
  • Tommaso Verdina

2 March 2024

Background: Hidradenitis suppurativa (HS) is a relapsing–remitting inflammatory disease characterized by the progression of asymptomatic nodules to deep-seated lesions and fistula formation that leads to suppuration and scarring. Optical cohere...