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8 Results Found

  • Article
  • Open Access
1 Citations
1,433 Views
5 Pages

The Effect of Nebulized Dorzolamide/Timolol Fixed Combination Mist versus Drops on Retrobulbar Blood Flow and Intraocular Pressure in Glaucoma Patients

  • Ingrida Janulevičienė,
  • Lina Šiaudvytytė,
  • Rūta Baršauskaitė,
  • Vaida Dilienė,
  • Loreta Kuzmienė,
  • Brent Siesky and
  • Alon Harris

4 August 2013

Objective. The aim of this study was to evaluate intraocular pressure (IOP), retrobulbar blood flow (RBF), and ocular side effects after the application of topical dorzolamide/timolol fixed combination (DTFC) drops vs topical nebulized DTFC mist in p...

  • Article
  • Open Access
1 Citations
6,337 Views
8 Pages

The Effect of Diluted Penetration Enhancer in Nebulized Mist versus Liquid Drop Preparation Forms on Retrobulbar Blood Flow in Healthy Human Subjects

  • Sally Primus,
  • Ingrida Januleviciene,
  • Brent Siesky,
  • Austin Gerber,
  • Patrick Egan,
  • Annahita Amireskandari,
  • Lina Siaudvytyte,
  • Ruta Barsauskaite and
  • Alon Harris

The aim of this study was to compare the effects of nebulized mist and liquid drop applications on retrobulbar blood flow. A prospective, non-randomized clinical trial was used to collect data from 40 healthy human eyes. Color Doppler Imaging determi...

  • Review
  • Open Access
7 Citations
5,115 Views
25 Pages

23 November 2023

Abnormal retrobulbar hemodynamics have been linked to the development of various ocular diseases, including glaucoma, age-related macular degeneration, and diabetic retinopathy. Additionally, altered retrobulbar blood flow has been observed in patien...

  • Article
  • Open Access
537 Views
14 Pages

Comparative Analysis of Retrobulbar Blood Flow in Symmetric and Asymmetric Keratoconus Patients

  • Fatma Huriye Kısa,
  • Hüseyin Findik,
  • Feyzahan Uzun,
  • Muhammet Kaim,
  • Merve Solak and
  • Mehmet Gökhan Aslan

12 August 2025

Background/Objectives: Keratoconus is a progressive corneal disorder characterized by thinning and conical protrusion of the cornea, resulting in visual impairment. This study aimed to evaluate retrobulbar blood flow characteristics in patients with...

  • Article
  • Open Access
5 Citations
8,099 Views
14 Pages

21 March 2012

Objective: To compare the effects of dorzolamide and timolol add-on therapy in open-angle glaucoma (OAG) patients previously treated with prostaglandin analogue (Pg), by evaluating fluctuations in the intraocular (IOP), blood (BP), ocular perfusion p...

  • Article
  • Open Access
3 Citations
1,149 Views
10 Pages

Relationship Between Intracranial Pressure, Ocular Blood Flow and Vessel Density: Insights from OCTA and Doppler Imaging

  • Arminas Zizas,
  • Keren Wood,
  • Austėja Judickaitė,
  • Vytautas Petkus,
  • Arminas Ragauskas,
  • Viktorija Bakstytė,
  • Alon Harris and
  • Ingrida Janulevičienė

25 April 2025

Background and Objectives: Despite the growing amount of new research, the pathophysiology of glaucoma remains unclear. The aim of this study was to determine the relationship between intracranial pressure (ICP), ocular blood flow and structural opti...

  • Article
  • Open Access
705 Views
16 Pages

Serotonin Signaling Pathway Modulation Affects Retinal Neuron Survival in Experimental Model of Retinal Ischemia

  • Joanna Machowicz,
  • Klaudia Mróz,
  • Anna Pacwa,
  • Anna Gąsiorek,
  • Piotr Rodak,
  • Joanna Lewin-Kowalik,
  • Marialaura Amadio and
  • Adrian Smędowski

8 November 2025

Serotonin is a key neurotransmitter involved in visual processing. Selective serotonin reuptake inhibitors (SSRIs), such as Escitalopram, enhance serotonergic transmission and exert neuroprotective effects. Although these actions are well established...

  • Article
  • Open Access
17 Citations
3,423 Views
9 Pages

Evaluation of Hemodynamic Changes in Retrobulbar Blood Vessels Using Color Doppler Imaging in Diabetic Patients

  • Gulshan Madhpuriya,
  • Sudheer Gokhale,
  • Alka Agrawal,
  • Prakhar Nigam and
  • Yung-Liang Wan

23 April 2022

Background—Diabetic retinopathy is a common complication of long-standing hyperglycemia. Microangiopathy-induced retinal changes are well-visualized on ophthalmoscopic examination. However, certain hemodynamic alterations have also been documen...