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MDPIMDPI

8 Results Found

  • Article
  • Open Access
14 Citations
2,592 Views
10 Pages
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Restrictive Atrial Dysfunction in Cardiac Amyloidosis: Differences between Immunoglobulin Light Chain and Transthyretin Cardiac Amyloidosis Patients

  • Mathijs O. Versteylen,
  • Maaike Brons,
  • Arco J. Teske and
  • Marish I. F. J. Oerlemans
Biomedicines2022, 10(8), 1768;https://doi.org/10.3390/biomedicines10081768

22 July 2022

Background: In cardiac amyloidosis, the prevalence of thromboembolic events and atrial fibrillation is higher in transthyretin amyloidosis compared to immunoglobulin light chain amyloidosis. Therefore, we hypothesize that transthyretin cardiac amyloi...

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  • Article
  • Open Access
39 Citations
5,558 Views
15 Pages
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Left Atrial Strain Imaging by Speckle Tracking Echocardiography: The Supportive Diagnostic Value in Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

  • Ines Paola Monte,
  • Denise Cristiana Faro,
  • Giancarlo Trimarchi,
  • Fabrizio de Gaetano,
  • Mariapaola Campisi,
  • Valentina Losi,
  • Lucio Teresi,
  • Gianluca Di Bella,
  • Corrado Tamburino and
  • Cesare de Gregorio
J. Cardiovasc. Dev. Dis.2023, 10(6), 261;https://doi.org/10.3390/jcdd10060261

15 June 2023

Background: Left atrial (LA) function is crucial for assessing left ventricular filling in various cardiovascular conditions. Cardiac Amyloidosis (CA) is characterized by atrial myopathy and LA function impairment, with diastolic dysfunction up to re...

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  • Article
  • Open Access
3 Citations
1 Views
7 Pages
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Atrial Fibrillation Is Poorly Tolerated by Patients with Hypertrophic Concentric Cardiomyopathy Caused by Mitochondrial tRNALeu (UUR) Mutations

  • Tiina M. Heliö,
  • Alexandra Götz,
  • Janne Rapola,
  • Sari Kiuru-Enari,
  • Sari Kivistö,
  • Terttu Heikinheimo and
  • Anu Suomalainen
Cardiogenetics2013, 3(1), e6;https://doi.org/10.4081/cardiogenetics.2013.e6

28 June 2013

Knowledge on the molecular background of mitochondrial disorders has accumulated during the past two decades, but clinical and molecular features of mitochondrial cardiomyopathies (CMPs) are only starting to be characterized. We studied the detailed...

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  • Review
  • Open Access
14 Citations
5,934 Views
22 Pages
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The Impact of Natriuretic Peptides on Heart Development, Homeostasis, and Disease

  • Alexandra E. Giovou,
  • Monika M. Gladka and
  • Vincent M. Christoffels
Cells2024, 13(11), 931;https://doi.org/10.3390/cells13110931

28 May 2024

During mammalian heart development, the clustered genes encoding peptide hormones, Natriuretic Peptide A (NPPA; ANP) and B (NPPB; BNP), are transcriptionally co-regulated and co-expressed predominately in the atrial and ventricular trabecular cardiom...

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  • Review
  • Open Access
23 Citations
5,077 Views
12 Pages
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Arrhythmic Manifestations of Cardiac Amyloidosis: Challenges in Risk Stratification and Clinical Management

  • Natallia Laptseva,
  • Valentina A. Rossi,
  • Isabella Sudano,
  • Rahel Schwotzer,
  • Frank Ruschitzka,
  • Andreas J. Flammer and
  • Firat Duru
J. Clin. Med.2023, 12(7), 2581;https://doi.org/10.3390/jcm12072581

29 March 2023

Amyloidosis is a systemic disease characterized by extracellular deposits of insoluble amyloid in various tissues and organs. Cardiac amyloidosis is a frequent feature of the disease, causing a progressive, restrictive type of cardiomyopathy, and is...

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  • Article
  • Open Access
48 Citations
5,270 Views
12 Pages
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Left Atrial Strain to Identify Diastolic Dysfunction in Children with Cardiomyopathies

  • Jolanda Sabatino,
  • Giovanni Di Salvo,
  • Costantina Prota,
  • Valentina Bucciarelli,
  • Manjit Josen,
  • Josefa Paredes,
  • Nunzia Borrelli,
  • Domenico Sirico,
  • Sanjay Prasad and
  • Piers E. F. Daubeney
  • + 2 authors
J. Clin. Med.2019, 8(8), 1243;https://doi.org/10.3390/jcm8081243

17 August 2019

Background: Left ventricular (LV) diastolic dysfunction (DD) carries worse prognosis in childhood. 2-dimensional (2-D) left atrial (LA) strain accurately categorizes DD in adults but its role in children is unknown. Thus, the aim of this study is to...

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  • Review
  • Open Access
1 Citations
4,412 Views
20 Pages
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Tissue Doppler Imaging in Acute and Critical Care: Enhancing Diagnostic Precision

  • Ugo Giulio Sisto,
  • Daniele Orso,
  • Davide Maione,
  • Francesco Venturelli and
  • Antonio De Luca
Medicina2025, 61(6), 1051;https://doi.org/10.3390/medicina61061051

6 June 2025

Background and Objectives: The introduction of portable ultrasound devices has transformed clinical practice in emergency medicine. Diagnostic accuracy and patient safety have been enhanced by point-of-care ultrasonography (POCUS), which has become a...

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  • Review
  • Open Access
134 Views
14 Pages
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Multimodal Diagnosis of Cardiac Amyloidosis: Integrating Imaging, Histochemistry, and Proteomics of Precise Typing

  • Jakub Kancerek,
  • Łukasz Zniszczoł,
  • Piotr Lewandowski and
  • Romuald Wojnicz
Int. J. Mol. Sci.2026, 27(2), 820;https://doi.org/10.3390/ijms27020820

14 January 2026

Amyloidosis is a group of disorders caused by extracellular deposition of insoluble fibrillar proteins, leading to progressive organ dysfunction. Cardiac amyloidosis is clinically significant, as myocardial infiltration results in restrictive cardiom...

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