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23 pages, 3283 KiB  
Article
Light-Driven Optimization of Exopolysaccharide and Indole-3-Acetic Acid Production in Thermotolerant Cyanobacteria
by Antonio Zuorro, Roberto Lavecchia, Karen A. Moncada-Jacome, Janet B. García-Martínez and Andrés F. Barajas-Solano
Sci 2025, 7(3), 108; https://doi.org/10.3390/sci7030108 (registering DOI) - 3 Aug 2025
Abstract
Cyanobacteria are a prolific source of bioactive metabolites with expanding applications in sustainable agriculture and biotechnology. This work explores, for the first time in thermotolerant Colombian isolates, the impact of light spectrum, photoperiod, and irradiance on the co-production of exopolysaccharides (EPS) and indole-3-acetic [...] Read more.
Cyanobacteria are a prolific source of bioactive metabolites with expanding applications in sustainable agriculture and biotechnology. This work explores, for the first time in thermotolerant Colombian isolates, the impact of light spectrum, photoperiod, and irradiance on the co-production of exopolysaccharides (EPS) and indole-3-acetic acid (IAA). Six strains from hot-spring environments were screened under varying blue:red (B:R) LED ratios and full-spectrum illumination. Hapalosiphon sp. UFPS_002 outperformed all others, reaching ~290 mg L−1 EPS and 28 µg mL−1 IAA in the initial screen. Response-surface methodology was then used to optimize light intensity and photoperiod. EPS peaked at 281.4 mg L−1 under a B:R ratio of 1:5 LED, 85 µmol m−2 s−1, and a 14.5 h light cycle, whereas IAA was maximized at 34.4 µg mL−1 under cool-white LEDs at a similar irradiance. The quadratic models exhibited excellent predictive power (R2 > 0.98) and a non-significant lack of fit, confirming the light regime as the dominant driver of metabolite yield. These results demonstrate that precise photonic tuning can selectively steer carbon flux toward either EPS or IAA, providing an energy-efficient strategy to upscale thermotolerant cyanobacteria for climate-resilient biofertilizers, bioplastics precursors, and other high-value bioproducts. Full article
(This article belongs to the Section Biology Research and Life Sciences)
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24 pages, 4301 KiB  
Article
Estimation of the Kinetic Coefficient of Friction of Asphalt Pavements Using the Top Topography Surface Roughness Power Spectrum
by Bo Sun, Haoyuan Luo, Yibo Rong and Yanqin Yang
Materials 2025, 18(15), 3643; https://doi.org/10.3390/ma18153643 (registering DOI) - 2 Aug 2025
Abstract
This study proposes a method for estimating the kinetic coefficient of friction (COF) for asphalt pavements by improving and applying Persson’s friction theory. The method utilizes the power spectral density (PSD) of the top surface topography instead of the full PSD to better [...] Read more.
This study proposes a method for estimating the kinetic coefficient of friction (COF) for asphalt pavements by improving and applying Persson’s friction theory. The method utilizes the power spectral density (PSD) of the top surface topography instead of the full PSD to better reflect the actual contact conditions. This approach avoids including deeper roughness components that do not contribute to real rubber–pavement contact due to surface skewness. The key aspect of the method is determining an appropriate cutting plane to isolate the top surface. Four cutting strategies were evaluated. Results show that the cutting plane defined at 0.5 times the root mean square (RMS) height exhibits the highest robustness across all pavement types, with the estimated COF closely matching the measured values for all four tested surfaces. This study presents an improved method for estimating the kinetic coefficient of friction (COF) of asphalt pavements by employing the power spectral density (PSD) of the top surface roughness, rather than the total surface profile. This refinement is based on Persson’s friction theory and aims to exclude the influence of deep surface irregularities that do not make actual contact with the rubber interface. The core of the method lies in defining an appropriate cutting plane to isolate the topographical features that contribute most to frictional interactions. Four cutting strategies were investigated. Among them, the cutting plane positioned at 0.5 times the root mean square (RMS) height demonstrated the best overall applicability. COF estimates derived from this method showed strong consistency with experimentally measured values across all four tested asphalt pavement surfaces, indicating its robustness and practical potential. Full article
(This article belongs to the Section Construction and Building Materials)
35 pages, 2730 KiB  
Review
Deep Learning and NLP-Based Trend Analysis in Actuators and Power Electronics
by Woojun Jung and Keuntae Cho
Actuators 2025, 14(8), 379; https://doi.org/10.3390/act14080379 (registering DOI) - 1 Aug 2025
Viewed by 62
Abstract
Actuators and power electronics are fundamental components of modern control systems, enabling high-precision functionality, enhanced energy efficiency, and sophisticated automation. This study investigates evolving research trends and thematic developments in these areas spanning the last two decades (2005–2024). This study analyzed 1840 peer-reviewed [...] Read more.
Actuators and power electronics are fundamental components of modern control systems, enabling high-precision functionality, enhanced energy efficiency, and sophisticated automation. This study investigates evolving research trends and thematic developments in these areas spanning the last two decades (2005–2024). This study analyzed 1840 peer-reviewed abstracts obtained from the Web of Science database using BERTopic modeling, which integrates transformer-based sentence embeddings with UMAP for dimensionality reduction and HDBSCAN for clustering. The approach also employed class-based TF-IDF calculations, intertopic distance visualization, and hierarchical clustering to clarify topic structures. The analysis revealed a steady increase in research publications, with a marked surge post-2015. From 2005 to 2014, investigations were mainly focused on established areas including piezoelectric actuators, adaptive control, and hydraulic systems. In contrast, the 2015–2024 period saw broader diversification into new topics such as advanced materials, robotic mechanisms, resilient systems, and networked actuator control through communication protocols. The structural topic analysis indicated a shift from a unified to a more differentiated and specialized spectrum of research themes. This study offers a rigorous, data-driven outlook on the increasing complexity and diversity of actuator and power electronics research. The findings are pertinent for researchers, engineers, and policymakers aiming to advance state-of-the-art, sustainable industrial technologies. Full article
(This article belongs to the Special Issue Power Electronics and Actuators—Second Edition)
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13 pages, 1217 KiB  
Article
Optimization Scheme for Modulation of Data Transmission Module in Endoscopic Capsule
by Meiyuan Miao, Chen Ye, Zhiping Xu, Laiding Zhao and Jiafeng Yao
Sensors 2025, 25(15), 4738; https://doi.org/10.3390/s25154738 (registering DOI) - 31 Jul 2025
Viewed by 87
Abstract
The endoscopic capsule is a miniaturized device used for medical diagnosis, which is less invasive compared to traditional gastrointestinal endoscopy and can reduce patient discomfort. However, it faces challenges in communication transmission, such as high power consumption, serious signal interference, and low data [...] Read more.
The endoscopic capsule is a miniaturized device used for medical diagnosis, which is less invasive compared to traditional gastrointestinal endoscopy and can reduce patient discomfort. However, it faces challenges in communication transmission, such as high power consumption, serious signal interference, and low data transmission rate. To address these issues, this paper proposes an optimized modulation scheme that is low-cost, low-power, and robust in harsh environments, aiming to improve its transmission rate. The scheme is analyzed in terms of the in-body channel. The analysis and discussion for the scheme in wireless body area networks (WBANs) are divided into three aspects: bit error rate (BER) performance, energy efficiency (EE), and spectrum efficiency (SE), and complexity. These correspond to the following issues: transmission rate, communication quality, and low power consumption. The results demonstrate that the optimized scheme is more suitable for improving the communication performance of endoscopic capsules. Full article
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11 pages, 2887 KiB  
Article
INTEGRAL/ISGRI Post 2024-Periastron View of PSR B1259-63
by Aleksei Kuzin, Denys Malyshev, Maria Chernyakova, Brian van Soelen and Andrea Santangelo
Universe 2025, 11(8), 254; https://doi.org/10.3390/universe11080254 - 31 Jul 2025
Viewed by 92
Abstract
PSR B1259-63/LS 2883 is a well-studied gamma-ray binary hosting a pulsar in a 3.4-year eccentric orbit around a Be-type star. Its non-thermal emission spans from radio to TeV energies, exhibiting a significant increase near the periastron passage. This paper is dedicated to the [...] Read more.
PSR B1259-63/LS 2883 is a well-studied gamma-ray binary hosting a pulsar in a 3.4-year eccentric orbit around a Be-type star. Its non-thermal emission spans from radio to TeV energies, exhibiting a significant increase near the periastron passage. This paper is dedicated to the analysis of INTEGRAL observations of the system following its last periastron passage in June 2024. We aim to study the spectral evolution of this gamma-ray binary in the soft (0.3–10 keV) and hard (30–300 keV) X-ray energy bands. We performed a joint analysis of the data taken by INTEGRAL/ISGRI in July–August 2024 and quasi-simultaneous Swift/XRT observations. The spectrum of the system in the 0.3–300 keV band is well described by an absorbed power law with a photon index of Γ=1.42±0.03. We place constraints on potential spectral curvature, limiting the break energy Eb>30 keV for ΔΓ>0.3 and cutoff energy Ecutoff>150 keV at a 95% confidence level. For one-zone leptonic emission models, these values correspond to electron distribution spectral parameters of Eb,e>0.8 TeV and Ecutoff,e>1.7 TeV, consistent with previous constraints derived by H.E.S.S. Full article
(This article belongs to the Section Compact Objects)
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16 pages, 2562 KiB  
Article
Harmonic and Interharmonic Measurement Method Using Two-Fold Compound Convolution Windows and Zoom Fast Fourier Transform
by Xiangui Xiao, Lei Zhao, Shengjun Zhou, Haijun Liu, Zhong Fu and Dan Hu
Energies 2025, 18(15), 4047; https://doi.org/10.3390/en18154047 - 30 Jul 2025
Viewed by 162
Abstract
With the rapidly increasing penetration of new energy resources, the power grid faces significant threats from harmonics. To measure and suppress these harmonics, numerous harmonic measurement methods have been proposed. However, accurately identifying the parameters of harmonics and interharmonics remains challenging. To address [...] Read more.
With the rapidly increasing penetration of new energy resources, the power grid faces significant threats from harmonics. To measure and suppress these harmonics, numerous harmonic measurement methods have been proposed. However, accurately identifying the parameters of harmonics and interharmonics remains challenging. To address this issue, we propose a new method that combines two-fold convolution windows and ZoomFFT. This method leverages the advantages of low side lobe peaks and high side lobe attenuation rates of compound convolution windows to suppress spectral leakage. Additionally, a six-spectral-line interpolation method is employed to correct the calculation results. Furthermore, ZoomFFT is utilized to locally amplify the spectrum, enabling the distinction between interharmonics and harmonics with closely spaced frequencies. The simulation results demonstrate that the proposed algorithm effectively identifies interharmonics with similar frequencies, outperforming single-window functions and ZoomFFT in terms of accuracy. Full article
(This article belongs to the Section F: Electrical Engineering)
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16 pages, 2860 KiB  
Article
Maritime Spectrum Sensing Based on Cyclostationary Features and Convolutional Neural Networks
by Xuan Geng and Boyu Hu
Entropy 2025, 27(8), 809; https://doi.org/10.3390/e27080809 - 28 Jul 2025
Viewed by 165
Abstract
For maritime cognitive radio networks (MCRN), spectrum sensing (SS) is challenging due to the movement of the sea, channel interference, and unstable link quality. Besides the basic sensing capabilities that are required, SS in MCRN also requires the ability to adapt to complex [...] Read more.
For maritime cognitive radio networks (MCRN), spectrum sensing (SS) is challenging due to the movement of the sea, channel interference, and unstable link quality. Besides the basic sensing capabilities that are required, SS in MCRN also requires the ability to adapt to complex and dynamic environments. By transforming spectrum sensing into a classification problem and leveraging cyclostationary features and Convolutional Neural Networks (CNN), This paper proposes a classification-guided TC2NND (Transfer Cyclostationary- feature and Convolutional Neural Networks Detection) spectrum sensing algorithm, which regards the maritime spectrum sensing as a classification problem. The TC2NND algorithm first classifies the received signal features by extracting cycle power spectrum (CPS) features using the FFT (Fast Fourier Transform) Accumulation Method (FAM), and then makes a judgment using a variety of C2NND decision models. The experimental results demonstrate that the proposed TC2NND algorithm could achieve a detection probability of 91.5% with a false-alarm probability of 5% at SNR = −10 dB, which significantly outperforms the conventional methods. Full article
(This article belongs to the Special Issue Space-Air-Ground-Sea Integrated Communication Networks)
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37 pages, 9111 KiB  
Article
Conformal On-Body Antenna System Integrated with Deep Learning for Non-Invasive Breast Cancer Detection
by Marwa H. Sharaf, Manuel Arrebola, Khalid F. A. Hussein, Asmaa E. Farahat and Álvaro F. Vaquero
Sensors 2025, 25(15), 4670; https://doi.org/10.3390/s25154670 - 28 Jul 2025
Viewed by 273
Abstract
Breast cancer detection through non-invasive and accurate techniques remains a critical challenge in medical diagnostics. This study introduces a deep learning-based framework that leverages a microwave radar system equipped with an arc-shaped array of six antennas to estimate key tumor parameters, including position, [...] Read more.
Breast cancer detection through non-invasive and accurate techniques remains a critical challenge in medical diagnostics. This study introduces a deep learning-based framework that leverages a microwave radar system equipped with an arc-shaped array of six antennas to estimate key tumor parameters, including position, size, and depth. This research begins with the evolutionary design of an ultra-wideband octagram ring patch antenna optimized for enhanced tumor detection sensitivity in directional near-field coupling scenarios. The antenna is fabricated and experimentally evaluated, with its performance validated through S-parameter measurements, far-field radiation characterization, and efficiency analysis to ensure effective signal propagation and interaction with breast tissue. Specific Absorption Rate (SAR) distributions within breast tissues are comprehensively assessed, and power adjustment strategies are implemented to comply with electromagnetic exposure safety limits. The dataset for the deep learning model comprises simulated self and mutual S-parameters capturing tumor-induced variations over a broad frequency spectrum. A core innovation of this work is the development of the Attention-Based Feature Separation (ABFS) model, which dynamically identifies optimal frequency sub-bands and disentangles discriminative features tailored to each tumor parameter. A multi-branch neural network processes these features to achieve precise tumor localization and size estimation. Compared to conventional attention mechanisms, the proposed ABFS architecture demonstrates superior prediction accuracy and interpretability. The proposed approach achieves high estimation accuracy and computational efficiency in simulation studies, underscoring the promise of integrating deep learning with conformal microwave imaging for safe, effective, and non-invasive breast cancer detection. Full article
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15 pages, 4409 KiB  
Article
Performance of Dual-Layer Flat-Panel Detectors
by Dong Sik Kim and Dayeon Lee
Diagnostics 2025, 15(15), 1889; https://doi.org/10.3390/diagnostics15151889 - 28 Jul 2025
Viewed by 215
Abstract
Background/Objectives: In digital radiography imaging, dual-layer flat-panel detectors (DFDs), in which two flat-panel detector layers are stacked with a minimal distance between the layers and appropriate alignment, are commonly used in material decompositions as dual-energy applications with a single x-ray exposure. DFDs also [...] Read more.
Background/Objectives: In digital radiography imaging, dual-layer flat-panel detectors (DFDs), in which two flat-panel detector layers are stacked with a minimal distance between the layers and appropriate alignment, are commonly used in material decompositions as dual-energy applications with a single x-ray exposure. DFDs also enable more efficient use of incident photons, resulting in x-ray images with improved noise power spectrum (NPS) and detection quantum efficiency (DQE) performances as single-energy applications. Purpose: Although the development of DFD systems for material decomposition applications is actively underway, there is a lack of research on whether single-energy applications of DFD can achieve better performance than the single-layer case. In this paper, we experimentally observe the DFD performance in terms of the modulation transfer function (MTF), NPS, and DQE with discussions. Methods: Using prototypes of DFD, we experimentally measure the MTF, NPS, and DQE of the convex combination of the images acquired from the upper and lower detector layers of DFD. To optimize DFD performance, a two-step image registration is performed, where subpixel registration based on the maximum amplitude response to the transform based on the Fourier shift theorem and an affine transformation using cubic interpolation are adopted. The DFD performance is analyzed and discussed through extensive experiments for various scintillator thicknesses, x-ray beam conditions, and incident doses. Results: Under the RQA 9 beam conditions of 2.7 μGy dose, the DFD with the upper and lower scintillator thicknesses of 0.5 mm could achieve a zero-frequency DQE of 75%, compared to 56% when using a single-layer detector. This implies that the DFD using 75 % of the incident dose of a single-layer detector can provide the same signal-to-noise ratio as a single-layer detector. Conclusions: In single-energy radiography imaging, DFD can provide better NPS and DQE performances than the case of the single-layer detector, especially at relatively high x-ray energies, which enables low-dose imaging. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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18 pages, 16222 KiB  
Article
Enhanced Photoelectrochemical Performance of 2D Bi2O3/TiO2 Heterostructure Film by Bi2S3 Surface Modification and Broadband Photodetector Application
by Lai Liu and Huizhen Yao
Materials 2025, 18(15), 3528; https://doi.org/10.3390/ma18153528 - 28 Jul 2025
Viewed by 267
Abstract
Photoelectrochemical devices have garnered extensive research attention in the field of smart and multifunctional photoelectronics, owing to their lightweight nature, eco-friendliness, and cost-effective manufacturing processes. In this work, Bi2S3/Bi2O3/TiO2 heterojunction film was successfully fabricated [...] Read more.
Photoelectrochemical devices have garnered extensive research attention in the field of smart and multifunctional photoelectronics, owing to their lightweight nature, eco-friendliness, and cost-effective manufacturing processes. In this work, Bi2S3/Bi2O3/TiO2 heterojunction film was successfully fabricated and functioned as the photoelectrode of photoelectrochemical devices. The designed Bi2S3/Bi2O3/TiO2 photoelectrochemical photodetector possesses a broad light detection spectrum ranging from 400 to 900 nm and impressive self-powered characteristics. At 0 V bias, the device exhibits an on/off current ratio of approximately 1.3 × 106. It achieves a commendable detectivity of 5.7 × 1013 Jones as subjected to a 0.8 V bias potential, outperforming both bare TiO2 and Bi2O3/TiO2 photoelectrochemical devices. Moreover, the Bi2S3/Bi2O3/TiO2 photoelectrode film shows great promise in pollutant decomposition, achieving nearly 97.7% degradation efficiency within 60 min. The appropriate band energy alignment and the presence of an internal electric field at the interface of the Bi2S3/Bi2O3/TiO2 film serve as a potent driving force for the separation and transport of photogenerated carriers. These findings suggest that the Bi2S3/Bi2O3/TiO2 heterojunction film could be a viable candidate as a photoelectrode material for the development of high-performance photoelectrochemical optoelectronic devices. Full article
(This article belongs to the Section Thin Films and Interfaces)
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20 pages, 529 KiB  
Article
Maximization of Average Achievable Rate for NOMA-UAV Dual-User Communication System Assisted by RIS
by Yuandong Liu, Jianbo Ji and Juan Yang
Electronics 2025, 14(15), 2993; https://doi.org/10.3390/electronics14152993 - 27 Jul 2025
Viewed by 169
Abstract
Non-orthogonal multiple access (NOMA) technology can effectively improve spectrum efficiency, unmanned aerial vehicle (UAV) communication has the advantage of flexible deployment, and reconfigurable intelligent surface (RIS) can intelligently control the wireless transmission environment. Traditional communication systems have problems such as limited coverage and [...] Read more.
Non-orthogonal multiple access (NOMA) technology can effectively improve spectrum efficiency, unmanned aerial vehicle (UAV) communication has the advantage of flexible deployment, and reconfigurable intelligent surface (RIS) can intelligently control the wireless transmission environment. Traditional communication systems have problems such as limited coverage and low spectrum efficiency in complex scenarios. However, a key challenge in deploying RIS-assisted NOMA-UAV communication systems lies in how to jointly optimize the UAV flight trajectory, power allocation strategy, and RIS phase offset to achieve the maximum average achievable rate for users. The non-convex nature of the optimization complicates the problem, making it challenging to find an efficient solution. Based on this, this paper presents a RIS-assisted NOMA-UAV communication system consisting of one UAV, one RIS, and two ground users. To achieve the maximum average rate for users, the UAV flight trajectory, power allocation strategy, and RIS phase offset are jointly optimized. For the non-convex problem, we decompose it into three sub-problems based on its inherent structural characteristics and use an alternating iterative approach to gradually converge to a feasible solution. The simulation results demonstrate that the proposed scheme offers significant advantages in the application scenario. Compared to other benchmark schemes, it delivers superior performance improvements to the communication system and offers higher practical value. Full article
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22 pages, 6689 KiB  
Article
Design and Implementation of a Sun Outage Simulation System with High Uniformity and Stray Light Suppression Capability
by Zhen Mao, Zhaohui Li, Yong Liu, Limin Gao and Jianke Zhao
Sensors 2025, 25(15), 4655; https://doi.org/10.3390/s25154655 - 27 Jul 2025
Viewed by 337
Abstract
To enable accurate evaluation of satellite laser communication terminals under solar outage interference, this paper presents the design and implementation of a solar radiation simulation system targeting the 1540–1560 nm communication band. The system reconstructs co-propagating interference conditions through standardized and continuously tunable [...] Read more.
To enable accurate evaluation of satellite laser communication terminals under solar outage interference, this paper presents the design and implementation of a solar radiation simulation system targeting the 1540–1560 nm communication band. The system reconstructs co-propagating interference conditions through standardized and continuously tunable output, based on high irradiance and spectral uniformity. A compound beam homogenization structure—combining a multimode fiber and an apodizator—achieves 85.8% far-field uniformity over a 200 mm aperture. A power–spectrum co-optimization strategy is introduced for filter design, achieving a spectral matching degree of 78%. The system supports a tunable output from 2.5 to 130 mW with a 50× dynamic range and maintains power control accuracy within ±0.9%. To suppress internal background interference, a BRDF-based optical scattering model is established to trace primary and secondary stray light paths. Simulation results show that by maintaining the surface roughness of key mirrors below 2 nm and incorporating a U-shaped reflective light trap, stray light levels can be reduced to 5.13 × 10−12 W, ensuring stable detection of a 10−10 W signal at a 10:1 signal-to-background ratio. Experimental validation confirms that the system can faithfully reproduce solar outage conditions within a ±3° field of view, achieving consistent performance in spectrum shaping, irradiance uniformity, and background suppression. The proposed platform provides a standardized and practical testbed for ground-based anti-interference assessment of optical communication terminals. Full article
(This article belongs to the Section Communications)
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14 pages, 2878 KiB  
Article
A Peak Current Mode Boost DC-DC Converter with Hybrid Spread Spectrum
by Xing Zhong, Jianhai Yu, Yongkang Shen and Jinghu Li
Micromachines 2025, 16(8), 862; https://doi.org/10.3390/mi16080862 - 26 Jul 2025
Viewed by 267
Abstract
The stable operation of micromachine systems relies on reliable power management, where DC-DC converters provide energy with high efficiency to extend operational endurance. However, these converters also constitute significant electromagnetic interference (EMI) sources that may interfere with the normal functioning of micro-electromechanical systems. [...] Read more.
The stable operation of micromachine systems relies on reliable power management, where DC-DC converters provide energy with high efficiency to extend operational endurance. However, these converters also constitute significant electromagnetic interference (EMI) sources that may interfere with the normal functioning of micro-electromechanical systems. This paper proposes a boost converter utilizing Pulse Width Modulation (PWM) with peak current mode control to address the EMI issues inherent in the switching operation of DC-DC converters. The converter incorporates a Hybrid Spread Spectrum (HSS) technique to effectively mitigate EMI noise. The HSS combines a 1.2 MHz pseudo-random spread spectrum with a 9.4 kHz triangular periodic spread spectrum. At a standard switching frequency of 2 MHz, the spread spectrum range is set to ±7.8%. Simulations conducted using a 0.5 μm Bipolar Complementary Metal-Oxide-Semiconductor Double-diffused Metal-Oxide-Semiconductor (BCD) process demonstrate that the HSS technique reduces EMI around the switching frequency by 12.29 dBμV, while the converter’s efficiency decreases by less than 1%. Full article
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18 pages, 5232 KiB  
Article
Analysis of the Characteristics of a Multi-Generation System Based on Geothermal, Solar Energy, and LNG Cold Energy
by Xinfeng Guo, Hao Li, Tianren Wang, Zizhang Wang, Tianchao Ai, Zireng Qi, Huarong Hou, Hongwei Chen and Yangfan Song
Processes 2025, 13(8), 2377; https://doi.org/10.3390/pr13082377 - 26 Jul 2025
Viewed by 255
Abstract
In order to reduce gas consumption and increase the renewable energy proportion, this paper proposes a poly-generation system that couples geothermal, solar, and liquid natural gas (LNG) cold energy to produce steam, gaseous natural gas, and low-temperature nitrogen. The high-temperature flue gas is [...] Read more.
In order to reduce gas consumption and increase the renewable energy proportion, this paper proposes a poly-generation system that couples geothermal, solar, and liquid natural gas (LNG) cold energy to produce steam, gaseous natural gas, and low-temperature nitrogen. The high-temperature flue gas is used to heat LNG; low-temperature flue gas, mainly nitrogen, can be used for cold storage cooling, enabling the staged utilization of the energy. Solar shortwave is used for power generation, and longwave is used to heat the working medium, which realizes the full spectrum utilization of solar energy. The influence of different equipment and operating parameters on the performance of a steam generation system is studied, and the multi-objective model of the multi-generation system is established and optimized. The results show that for every 100 W/m2 increase in solar radiation, the renewable energy ratio of the system increases by 1.5%. For every 10% increase in partial load rate of gas boiler, the proportion of renewable energy decreases by 1.27%. The system’s energy efficiency, cooling output, and the LNG vaporization flow rate are negatively correlated with the scale of solar energy utilization equipment. The decision variables determined by the TOPSIS (technique for order of preference by similarity to ideal solution) method have better economic performance. Its investment cost is 18.14 × 10 CNY, which is 7.83% lower than that of the LINMAP (linear programming technique for multidimensional analysis of preference). Meanwhile, the proportion of renewable energy is only 0.29% lower than that of LINMAP. Full article
(This article belongs to the Special Issue Innovations in Waste Heat Recovery in Industrial Processes)
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55 pages, 4973 KiB  
Review
Zebrafish as a Model Organism for Post-Traumatic Stress Disorder: Insights into Stress Mechanisms and Behavioral Assays
by Alexey Sarapultsev, Maria Komelkova, Oleg Lookin, Sergey Khatsko, Alexander Zhdanov, Stanislav Fedorov, Evgenii Gusev, Alexander Trofimov, Tursonjan Tokay and Desheng Hu
Biology 2025, 14(8), 939; https://doi.org/10.3390/biology14080939 - 25 Jul 2025
Viewed by 274
Abstract
The zebrafish (Danio rerio) has emerged as a powerful model organism for investigating the mechanisms of post-traumatic stress disorder (PTSD), offering unique advantages in translational relevance, genetic trackability, and cost-effectiveness. As a logical continuation of our recent systematic review, this manuscript [...] Read more.
The zebrafish (Danio rerio) has emerged as a powerful model organism for investigating the mechanisms of post-traumatic stress disorder (PTSD), offering unique advantages in translational relevance, genetic trackability, and cost-effectiveness. As a logical continuation of our recent systematic review, this manuscript critically examines the spectrum of experimental strategies used to model PTSD in zebrafish, with a focus on the comparative efficacy and validity of acute, chronic, and complex stress paradigms. Among these, 14–15-day chronic unpredictable stress (CUS/UCS) protocols are identified as the gold standard, reliably inducing core PTSD-like phenotypes—such as anxiety-like behavior, cortisol dysregulation, and neuroinflammatory gene activation. We discuss the influence of environmental, developmental, and genetic factors on stress responses, and highlight the importance of standardized behavioral and molecular endpoints for model validation. While alternative paradigms—including acute, social, pharmacological, and predator-based models—offer mechanistic insights, their translational relevance remains limited without further refinement. We conclude by outlining future directions for zebrafish-based PTSD research, emphasizing the need for protocol harmonization, integration of multi-modal readouts, and exploration of individual variability to enhance the translational value of this model system. Full article
(This article belongs to the Special Issue Social Behavior in Zebrafish)
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