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5 Results Found

  • Article
  • Open Access
30 Citations
5,980 Views
18 Pages

Freeze-Dried Mesenchymal Stem Cell-Secretome Pharmaceuticalization: Optimization of Formulation and Manufacturing Process Robustness

  • Michela Mocchi,
  • Elia Bari,
  • Giorgio Marrubini,
  • Andrea Foglio Bonda,
  • Sara Perteghella,
  • Fulvio Tartara,
  • Fabio Cofano,
  • Giuseppe di Perna,
  • Lorella Giovannelli and
  • Lorena Segale
  • + 4 authors

Producing mesenchymal stem cell (MSC)-secretome for dose escalation studies and clinical practice requires scalable and good manufacturing practice (GMP)-compliant production procedures and formulation into a standardized medicinal product. Starting...

  • Concept Paper
  • Open Access
3 Citations
8,334 Views
51 Pages

13 August 2022

This article seeks to capture variations and tensions in the relationships between the health–illness–medicine complex and society. It presents several theoretical reconstructions, established theses and arguments are reassessed and criti...

  • Article
  • Open Access
4 Citations
6,344 Views
16 Pages

With rapidly increasing rates of non-communicable diseases, India is experiencing a dramatic public health crisis that is closely linked to changing lifestyles and the growth of the middle-class. In this essay we discuss how the practice of Nature Cu...

  • Review
  • Open Access
52 Citations
8,012 Views
26 Pages

Veterinary Regenerative Medicine for Musculoskeletal Disorders: Can Mesenchymal Stem/Stromal Cells and Their Secretome Be the New Frontier?

  • Michela Mocchi,
  • Silvia Dotti,
  • Maurizio Del Bue,
  • Riccardo Villa,
  • Elia Bari,
  • Sara Perteghella,
  • Maria Luisa Torre and
  • Stefano Grolli

11 June 2020

Regenerative medicine aims to restore the normal function of diseased or damaged cells, tissues, and organs using a set of different approaches, including cell-based therapies. In the veterinary field, regenerative medicine is strongly related to the...

  • Discussion
  • Open Access
8 Citations
5,596 Views
13 Pages

Looking for the “Little Things”: A Multi-Disciplinary Approach to Medicines Monitoring for Older People Using the ADRe Resource

  • David Hughes,
  • Meirion Jordan,
  • Patricia A. Logan,
  • Alan Willson,
  • Sherrill Snelgrove,
  • Melanie Storey,
  • Mojtaba Vaismoradi and
  • Sue Jordan

Advances in medicines have increased the effectiveness of treatments and the social and cultural authority of doctors. However, as prescribing has become the dominant modality of treatment, the “pharmaceuticalization” of medical practice...