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9 Results Found

  • Article
  • Open Access
13 Citations
7,015 Views
18 Pages

11 June 2014

Two new multi-component molecular complexes of cytosine and 5-fluorocytosine with 4-chloro-3,5-dinitrobenzoic acid are presented. Materials synthesis was achieved initially by evaporative crystallisation and the crystal structures determined. The pro...

  • Article
  • Open Access
2 Citations
2,267 Views
16 Pages

pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions

  • Mª Carmen Salinas-García,
  • Marina Plaza-Garrido,
  • Jose A. Gavira,
  • Javier Murciano-Calles,
  • Montserrat Andújar-Sánchez,
  • Emilia Ortiz-Salmerón,
  • Jose C. Martinez and
  • Ana Cámara-Artigas

24 January 2023

The PDZ domains are modular domains that recognise short linear C-terminal sequences in proteins that organise the formation of complex multi-component assemblies. We have crystallised the third PDZ domain of the neuronal postsynaptic density-95 prot...

  • Proceeding Paper
  • Open Access
1 Citations
2,945 Views
10 Pages

1 December 2020

Multicomponent crystallisation is a widely studied technique in pharmaceutical chemistry to enhance physical properties of API’s such as solubility, stability and bioavailability without chemically modifying the drug moiety itself. Methods to produce...

  • Review
  • Open Access
7 Citations
2,950 Views
21 Pages

7 June 2023

Phthalocyanines (Pcs) are 18-electron π-conjugated macrocyclic ring systems with proven activities in diverse fields, including pharmaceuticals and catalysis. These demonstrated activities are often alluded to as their fascinating photophysical an...

  • Article
  • Open Access
3 Citations
2,520 Views
16 Pages

Halogen Bonding in Sulphonamide Co-Crystals: X···π Preferred over X···O/N?

  • Tobias Heinen,
  • Sarah Merzenich,
  • Angelina Kwill and
  • Vera Vasylyeva

6 August 2023

Sulphonamides have been one of the major pharmaceutical compound classes since their introduction in the 1930s. Co-crystallisation of sulphonamides with halogen bonding (XB) might lead to a new class of pharmaceutical-relevant co-crystals. We present...

  • Article
  • Open Access
3 Citations
1,792 Views
25 Pages

Thermo-Physical Behaviour of Thermoplastic Composite Pipe for Oil and Gas Applications

  • Obinna Okolie,
  • Nadimul Haque Faisal,
  • Harvey Jamieson,
  • Arindam Mukherji and
  • James Njuguna

19 April 2025

Thermoplastic composite pipes (TCP) consist of three distinct layers—liner, reinforcement, and coating—offering superior advantages over traditional industrial pipes, including flexibility, lightweight construction, and corrosion resistan...

  • Article
  • Open Access
8 Citations
3,157 Views
15 Pages

Assessing the Viability of Integrating Evaporation and Solvent Extraction Systems for Lithium Recovery from Low-Grade Brines

  • Katarzyna Ochromowicz,
  • Monika Zabłocka-Malicka,
  • Ida Chojnacka and
  • Magdalena Worsa-Kozak

11 July 2024

In recent years, the demand for lithium, essential to the high-tech and battery sectors, has increased rapidly. The majority of lithium carbonate is now sourced from continental brines in Latin America, owing to the lower production costs and reduced...

  • Article
  • Open Access
1,457 Views
23 Pages

Magmatic Evolution and Nb-Ta Enrichment of Early Jurassic Granitic Porphyry from the Shangxiahu Nb-Ta Deposit of the Nanling Range

  • Hongling Liu,
  • Jinrong Wang,
  • Qin Chen,
  • Yanna Huang,
  • Xin Li,
  • Wei Liu,
  • Bin Chen and
  • Fan Xiao

3 October 2024

The Shangxiahu Nb-Ta deposit is located in the Yongding region of Fujian Province, the south-eastern section of the Nanling Range, South China. A series of Nb-Ta deposits, associated with granitic porphyries, are present in the Yongding region. Never...

  • Article
  • Open Access
9 Citations
4,233 Views
33 Pages

Halogens in Eclogite Facies Minerals from the Western Gneiss Region, Norway

  • Lewis Hughes,
  • Simon Cuthbert,
  • Alex Quas-Cohen,
  • Lorraine Ruzié-Hamilton,
  • Alison Pawley,
  • Giles Droop,
  • Ian Lyon,
  • Romain Tartèse and
  • Ray Burgess

14 July 2021

Ultra-high-pressure (UHP) eclogites and ultramafites and associated fluid inclusions from the Western Gneiss Region, Norwegian Caledonides, have been analysed for F, Cl, Br and I using electron-probe micro-analysis, time-of-flight secondary ion mass...