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Article

21 Citations

5,860 Views

14 Pages

Doxorubicin Loaded PLGA Nanoparticle with Cationic/Anionic Polyelectrolyte Decoration: Characterization, and Its Therapeutic Potency

Li-Hui Tsai,
Chia-Hsiang Yen,
Hao-Ying Hsieh and
Tai-Horng Young

Polymers2021, 13(5), 693;https://doi.org/10.3390/polym13050693

25 February 2021

Optimized Doxorubicin hydrochloride (DOX) loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles (DPN) were prepared by controlling the water/oil distribution of DOX at different pH solutions and controlling the electrostatic interaction between D...

(This article belongs to the Section Biobased and Biodegradable Polymers)

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Article

2 Citations

1,308 Views

15 Pages

In-Situ Forming Polyester Implants for Sustained Intravesical Oxybutynin Release

Michael Uwe Hartig,
Jan Appelhaus,
Marc Vollenbröker and
Alf Lamprecht

Pharmaceutics2025, 17(11), 1369;https://doi.org/10.3390/pharmaceutics17111369

23 October 2025

Background/Objectives: Neurogenic detrusor overactivity (NDO), caused by spinal cord injury or multiple sclerosis, is marked by involuntary bladder contractions and reduced urine volume. Current therapy requires frequent catheterization with oxybutyn...

(This article belongs to the Section Drug Delivery and Controlled Release)

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