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  • Article
  • Open Access
37 Citations
12,571 Views
20 Pages

RETRACTED: Fluorinated Analogs of Organosulfur Compounds from Garlic (Allium sativum): Synthesis, Chemistry and Anti-Angiogenesis and Antithrombotic Studies

  • Eric Block,
  • Benjamin Bechand,
  • Sivaji Gundala,
  • Abith Vattekkatte,
  • Kai Wang,
  • Shaymaa S. Mousa,
  • Kavitha Godugu,
  • Murat Yalcin and
  • Shaker A. Mousa

28 November 2017

We describe the synthesis, reactivity, and antithrombotic and anti-angiogenesis activity of difluoroallicin (S-(2-fluoroallyl) 2-fluoroprop-2-ene-1-sulfinothioate) and S-2-fluoro-2-propenyl-l-cysteine, both easily prepared from commercially available...

(This article belongs to the Special Issue The Chemistry of Alliums)
  • Article
  • Open Access
2 Citations
1,668 Views
13 Pages

Fluorinated Analogs of Organosulfur Compounds from Garlic (Allium sativum): Synthesis and Chemistry

  • Eric Block,
  • Benjamin Bechand,
  • Sivaji Gundala,
  • Abith Vattekkatte and
  • Kai Wang

We report the first syntheses—from commercially available 3-chloro-2-fluoroprop-1-ene (9)—of key garlic-derived compounds containing sp2-fluorine. We also report synthesis of fluoro-5,6-dihydrothiopyrans by trapping 2-fluorothioacrolein (...