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Article

20 Citations

7,375 Views

13 Pages

UHPLC-UV Method for Simultaneous Determination of Perindopril Arginine and Indapamide Hemihydrate in Combined Dosage Form: A Stability-Indicating Assay Method

Naser F. Al-Tannak

Sci. Pharm.2018, 86(1), 7;https://doi.org/10.3390/scipharm86010007

22 February 2018

Perindopril arginine and Indapamide hemihydrate in combination were proven to have a synergistic antihypertensive impact when compared with the use of each component alone. Therefore, a new Ultra-High Performance Liquid Chromatography coupled with Ul...

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Article

6 Citations

5,133 Views

12 Pages

Permeability of the Perindopril Arginine under In Vitro Conditions across Caco-2 Monolayer and Biomimetic Phospholipid Membrane

Marta Kus,
Klaudia Gorniak,
Piotr Czaklosz,
Anna Olejnik,
Paulina Skupin-Mrugalska,
Izabela Ibragimow and
Hanna Piotrowska-Kempisty

Molecules2022, 27(7), 2232;https://doi.org/10.3390/molecules27072232

30 March 2022

Perindopril arginine (PA) as an angiotensin-converting enzyme (ACE) inhibitor is widely used in cardiovascular diseases, especially in systemic hypertension and heart failure. Although the pharmacokinetics of PA are well documented, there is no avail...

(This article belongs to the Special Issue Drug Delivery Systems for Overcoming the Biological Barriers and Improving the Therapeutic Effect)

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