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3 Results Found

  • Article
  • Open Access
62 Citations
8,818 Views
16 Pages

Myocardial Ischemic Postconditioning Promotes Autophagy against Ischemia Reperfusion Injury via the Activation of the nNOS/AMPK/mTOR Pathway

  • Maojuan Hao,
  • Suhua Zhu,
  • Liang Hu,
  • Hongyi Zhu and ,
  • Xiaowei Wu and
  • Qingping Li
  • + 1 author+ 0 author

Autophagy participates in the progression of many diseases, comprising ischemia/ reperfusion (I/R). It is reported that it is involved in the protective mechanism of ischemic postconditioning (IPostC). According to research, neuronal nitric oxide syn...

(This article belongs to the Special Issue Improvement of Cardiac Function in Heart Failure 2017)
  • Article
  • Open Access
9 Citations
3,619 Views
20 Pages

Ischemic Postconditioning Regulates New Cell Death Mechanisms in Stroke: Disulfidptosis

  • Shanpeng Liu,
  • Qike Wu,
  • Can Xu,
  • Liping Wang and ,
  • Jialing Wang,
  • Cuiying Liu and
  • Heng Zhao
  • + 2 authors+ 0 author

31 October 2024

Background and Objective: Stroke poses a critical health issue without effective neuroprotection. We explore ischemic postconditioning’s (IPostC) potential to mitigate stroke-induced brain injury, focusing on its interaction with disulfidptosis...

(This article belongs to the Special Issue Molecular and Cellular Mechanisms of Ischemic Stroke)
  • Article
  • Open Access
14 Citations
5,704 Views
19 Pages

Transcriptional Alterations by Ischaemic Postconditioning in a Pig Infarction Model: Impact on Microvascular Protection

  • Dominika Lukovic,
  • Alfred Gugerell,
  • Katrin Zlabinger,
  • Johannes Winkler and ,
  • Noemi Pavo,
  • Tamás Baranyai,
  • Zoltán Giricz,
  • Zoltán V. Varga,
  • Martin Riesenhuber and
  • Mariann Gyöngyösi
  • + 14 authors+ 9 authors

Although the application of cardioprotective ischaemia/reperfusion (I/R) stimuli after myocardial infarction (MI) is a promising concept for salvaging the myocardium, translation to a clinical scenario has not fulfilled expectations. We have previous...

(This article belongs to the Special Issue Novel Molecular Targets for Cardioprotection: The EU-CARDIOPROTECTION COST Action (CA16225))