You are currently on the new version of our website. Access the old version .

7 Results Found

  • Article
  • Open Access
20 Citations
11,165 Views
14 Pages

Fossilized Venom: The Unusually Conserved Venom Profiles of Heloderma Species (Beaded Lizards and Gila Monsters)

  • Ivan Koludarov,
  • Timothy N. W. Jackson,
  • Kartik Sunagar,
  • Amanda Nouwens,
  • Iwan Hendrikx and
  • Bryan G. Fry

22 December 2014

Research into snake venoms has revealed extensive variation at all taxonomic levels. Lizard venoms, however, have received scant research attention in general, and no studies of intraclade variation in lizard venom composition have been attempted to...

  • Article
  • Open Access
10 Citations
7,791 Views
14 Pages

The Dragon’s Paralysing Spell: Evidence of Sodium and Calcium Ion Channel Binding Neurotoxins in Helodermatid and Varanid Lizard Venoms

  • James S. Dobson,
  • Richard J. Harris,
  • Christina N. Zdenek,
  • Tam Huynh,
  • Wayne C. Hodgson,
  • Frank Bosmans,
  • Rudy Fourmy,
  • Aude Violette and
  • Bryan G. Fry

6 August 2021

Bites from helodermatid lizards can cause pain, paresthesia, paralysis, and tachycardia, as well as other symptoms consistent with neurotoxicity. Furthermore, in vitro studies have shown that Heloderma horridum venom inhibits ion flux and blocks the...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,179 Views
24 Pages

The Clot Thickens: Differential Coagulotoxic and Cardiotoxic Activities of Anguimorpha Lizard Venoms

  • James Dobson,
  • Abhinandan Chowdhury,
  • Jeremie Tai-A-Pin,
  • Harold van der Ploeg,
  • Amber Gillett and
  • Bryan G. Fry

20 June 2024

Despite their evolutionary novelty, lizard venoms are much less studied in comparison to the intense research on snake venoms. While the venoms of helodermatid lizards have long been assumed to be for defensive purposes, there is increasing evidence...

  • Article
  • Open Access
24 Citations
10,545 Views
13 Pages

Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage

  • James S. Dobson,
  • Christina N. Zdenek,
  • Chris Hay,
  • Aude Violette,
  • Rudy Fourmy,
  • Chip Cochran and
  • Bryan G. Fry

7 May 2019

The functional activities of Anguimorpha lizard venoms have received less attention compared to serpent lineages. Bite victims of varanid lizards often report persistent bleeding exceeding that expected for the mechanical damage of the bite. Research...

  • Article
  • Open Access
43 Citations
34,613 Views
37 Pages

Enter the Dragon: The Dynamic and Multifunctional Evolution of Anguimorpha Lizard Venoms

  • Ivan Koludarov,
  • Timothy NW Jackson,
  • Bianca op den Brouw,
  • James Dobson,
  • Daniel Dashevsky,
  • Kevin Arbuckle,
  • Christofer J. Clemente,
  • Edward J. Stockdale,
  • Chip Cochran and
  • Bryan G. Fry
  • + 12 authors

6 August 2017

While snake venoms have been the subject of intense study, comparatively little work has been done on lizard venoms. In this study, we have examined the structural and functional diversification of anguimorph lizard venoms and associated toxins, and...

  • Article
  • Open Access
14 Citations
6,102 Views
17 Pages

Behavioral Assessment of Six Reptile Species during a Temporary Zoo Closure and Reopening

  • Jennifer Hamilton,
  • Kylen N. Gartland,
  • Megan Jones and
  • Grace Fuller

15 April 2022

Although reptiles are commonly housed in zoos and aquariums, their welfare is understudied for the diversity of species housed and the taxon’s current captive population size. The sensory abilities of reptiles have adapted to the varied ecologi...

  • Article
  • Open Access
2 Citations
6,493 Views
21 Pages

New Lizard Specimens from the Campanian Wapiti Formation of Alberta, Canada

  • Samantha M. Hamilton,
  • Ilaria Paparella,
  • Phil R. Bell,
  • Nicolás E. Campione,
  • Federico Fanti,
  • Derek W. Larson,
  • Robin L. Sissons,
  • Matthew J. Vavrek,
  • Michael J. Balsai and
  • Corwin Sullivan

3 November 2023

Reported lizard material from the Wapiti Formation (central-western Alberta, Canada) is limited to fragmentary remains of Kleskunsaurus grandeprairiensis and Socognathus unicuspis, a partial dentary attributed to Chamops cf. C. segnis, and a vertebra...