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6 Results Found

  • Article
  • Open Access
1 Citations
4,194 Views
13 Pages

Activity of Epsilon-poly-L-lysine against Multidrug-Resistant Pseudomonas aeruginosa and Klebsiella pneumoniae Isolates of Urinary Tract Infections

  • Telma de Sousa,
  • Carolina Sabença,
  • Miguel Ribeiro,
  • Mario Pino-Hurtado,
  • Carmen Torres,
  • Michel Hébraud,
  • Olimpia Alves,
  • Sara Sousa,
  • Eliana Costa and
  • Gilberto Igrejas
  • + 1 author

Pseudomonas aeruginosa and Klebsiella pneumoniae are notorious for their resistance to antibiotics and propensity for biofilm formation, posing significant threats to human health. Epsilon-poly-L-lysine (ε-PL) emerges as a naturally occurring...

  • Article
  • Open Access
963 Views
18 Pages

Physiological Insights into Enhanced Epsilon-Poly-l-Lysine Production Induced by Extract Supplement from Heterogeneous Streptomyces Strain

  • Siyu Tong,
  • Chen Zhang,
  • Zhanyang Zhang,
  • Huawei Zeng,
  • Bingyue Xin,
  • Mingtao Zhao,
  • Deyin Zhao,
  • Xin Zeng and
  • Fei Zhang

Epsilon-poly-l-lysine (ε-PL) is a potent antimicrobial agent, but strategies to enhance its biosynthesis remain limited due to insufficient understanding of its physiological regulation. This study explores the interaction between Streptomyce...

  • Article
  • Open Access
13 Citations
3,281 Views
18 Pages

Silver and Antimicrobial Polymer Nanocomplexes to Enhance Biocidal Effects

  • Diana Pereira,
  • Susana Ferreira,
  • Gloria Belén Ramírez-Rodríguez,
  • Nuno Alves,
  • Ângela Sousa and
  • Joana F. A. Valente

19 January 2024

Antimicrobial resistance has become a major problem over the years and threatens to remain in the future, at least until a solution is found. Silver nanoparticles (Ag-NPs) and antimicrobial polymers (APs) are known for their antimicrobial properties...

  • Article
  • Open Access
33 Citations
5,239 Views
12 Pages

Evaluation of an Analogue of the Marine ε-PLL Peptide as a Ligand of G-quadruplex DNA Structures

  • Maria Marzano,
  • Andrea Patrizia Falanga,
  • Daniela Marasco,
  • Nicola Borbone,
  • Stefano D’Errico,
  • Gennaro Piccialli,
  • Giovanni Nicola Roviello and
  • Giorgia Oliviero

11 January 2020

ε-poly-l-Lysine (ε-PLL) peptide is a product of the marine bacterium Bacillus subtilis with antibacterial and anticancer activity largely used worldwide as a food preservative. ε-PLL and its synthetic analogue α,&epsilon...

  • Article
  • Open Access
3 Citations
2,991 Views
13 Pages

Biocontrol Microneedle Patch: A Promising Agent for Protecting Citrus Fruits from Postharvest Infection

  • Ling Jiang,
  • Huan Huang,
  • Xingyu Shi,
  • Jian Wu,
  • Juexian Ye,
  • Qian Xu,
  • Shaobin Fang,
  • Chuanbin Wu,
  • Rui Luo and
  • Chao Lu
  • + 1 author

With increasing human awareness of food safety, the replacement of highly toxic pesticides with biocompatible antimicrobials has become a trend. This study proposes a biocontrol microneedle (BMN) to expand the application of the food-grade preservati...

  • Article
  • Open Access
20 Citations
4,153 Views
21 Pages

Inactivation of Polymicrobial Biofilms of Foodborne Pathogens Using Epsilon Poly-L-Lysin Conjugated Chitosan Nanoparticles

  • Xingjian Bai,
  • Luping Xu,
  • Atul Kumar Singh,
  • Xiaoling Qiu,
  • Mai Liu,
  • Ahmed Abuzeid,
  • Talaat El-Khateib and
  • Arun K. Bhunia

16 February 2022

A mixed culture (polymicrobial) biofilm provides a favorable environment for pathogens to persist in the food processing environment and to contaminate food products. Inactivation and eradication of such biofilms from food processing environments are...