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Article

25 Citations

4,550 Views

17 Pages

Sulfate-Reducing Bacteria Induce Pro-Inflammatory TNF-α and iNOS via PI3K/Akt Pathway in a TLR 2-Dependent Manner

Sudha B. Singh,
Cody A. Braun,
Amanda Carroll-Portillo,
Cristina N. Coffman and
Henry C. Lin

Microorganisms2024, 12(9), 1833;https://doi.org/10.3390/microorganisms12091833

5 September 2024

Desulfovibrio, resident gut sulfate-reducing bacteria (SRB), are found to overgrow in diseases such as inflammatory bowel disease and Parkinson’s disease. They activate a pro-inflammatory response, suggesting that Desulfovibrio may play a causa...

(This article belongs to the Special Issue Advances in Host-Gut Microbiota)

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Article

941 Views

14 Pages

Rapamycin Prevents Sulfate-Reducing Bacteria-Induced Effects on Snail and GSK-3 and Impaired Intestinal Barrier

Sudha B. Singh,
Cody A. Braun,
Amanda Carroll-Portillo and
Henry C. Lin

Microorganisms2026, 14(4), 781;https://doi.org/10.3390/microorganisms14040781

30 March 2026

Desulfovibrio spp. are sulfate-reducing bacteria (SRB) associated with conditions such as inflammatory bowel disease (IBD) that are linked to intestinal barrier dysfunction (leaky gut). Previously, we reported that Desulfovibrio vulgaris (DSV) caused...

(This article belongs to the Special Issue The Microbial Pathogenesis)

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