The Microbial Pathogenesis

Dear Colleagues,

Microbial pathogenesis is a rapidly evolving field that explores the intricate interactions between microbial pathogens and their hosts. It encompasses the molecular mechanisms through which bacteria, viruses, fungi, and parasites invade host tissues, evade immune responses, and cause disease. Recent advances in genomics, transcriptomics, and systems biology have enabled deeper insights into microbial virulence factors, host–pathogen signaling pathways, and mechanisms of resistance and persistence. Understanding these processes is essential not only for developing new antimicrobial therapies and vaccines but also for advancing diagnostic and prognostic tools in clinical microbiology.

This Special Issue aims to highlight recent progress in the study of microbial pathogenesis across diverse pathogens and disease systems. We welcome original research articles, reviews, and short communications addressing molecular virulence mechanisms, host immune modulation, pathogen evolution, antibiotic resistance, and novel approaches for prevention and therapy. Studies employing cutting-edge techniques such as whole-genome sequencing, CRISPR-Cas, multi-omics integration, or in vivo infection models are particularly encouraged. Contributions from interdisciplinary fields such as microbiology, immunology, molecular biology, and clinical research are also welcome.

We look forward to your submissions.

Dr. Tingting Wang
Guest Editor

Dr. Canfeng Hua
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.