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11 Results Found

  • Article
  • Open Access
66 Citations
12,423 Views
18 Pages

18 January 2020

Morinda citrifolia, a fruit generally known as “Noni”, has been traditionally used in parts of East Asia to relieve inflammatory diseases. Although several studies using noni have been reported, the effect of fermented Morinda citrifolia...

  • Article
  • Open Access
18 Citations
5,100 Views
12 Pages

27 January 2019

Pyrus ussuriensis Maxim, a pear commonly known as “Sandolbae” in Korea, is used as a traditional herbal medicine for asthma, cough, and fever in Korea, China, and Japan. P. ussuriensis Maxim leaves (PUL) have therapeutic effects on atopic dermatitis...

  • Article
  • Open Access
24 Citations
6,708 Views
14 Pages

Oral Administration of Sargassum horneri Improves the HDM/DNCB-Induced Atopic Dermatitis in NC/Nga Mice

  • Eui Jeong Han,
  • Ilekuttige Priyan Shanura Fernando,
  • Hyun-Soo Kim,
  • You-Jin Jeon,
  • Dissanayaka Mudiyanselage Dinesh Madusanka,
  • Mawalle Kankanamge Hasitha Madhawa Dias,
  • Youngheun Jee and
  • Ginnae Ahn

18 August 2020

The present study investigated the protective effects of Sargassum horneri (S. horneri) ethanol extract (SHE) against atopic dermatitis (AD), known as an abnormal immune response in house dust mite (HDM)/2,4-dinitrochlorobenzene (DNCB)-stimulated NC/...

  • Article
  • Open Access
23 Citations
5,166 Views
11 Pages

Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression

  • Hyeong Rok Yun,
  • Sang Woo Ahn,
  • Bomin Seol,
  • Elena A. Vasileva,
  • Natalia P. Mishchenko,
  • Sergey A. Fedoreyev,
  • Valentin A. Stonik,
  • Jin Han,
  • Kyung Soo Ko and
  • Byoung Doo Rhee
  • + 2 authors

1 November 2021

Atopic dermatitis (AD) is a chronic inflammatory skin disease in which skin barrier dysfunction leads to dryness, pruritus, and erythematous lesions. AD is triggered by immune imbalance and oxidative stress. Echinochrome A (Ech A), a natural pigment...

  • Article
  • Open Access
35 Citations
7,507 Views
12 Pages

Effect of Resveratrol-Enriched Rice on Skin Inflammation and Pruritus in the NC/Nga Mouse Model of Atopic Dermatitis

  • Min Cheol Kang,
  • Kyohee Cho,
  • Jae Hyuk Lee,
  • Lalita Subedi,
  • Silvia Yumnam and
  • Sun Yeou Kim

Resveratrol-enriched rice (RR) was developed using genetic engineering to combine the properties of resveratrol and rice. To evaluate the effect of RR on pruritic skin inflammation in atopic dermatitis (AD)-like skin lesions, we used dinitrochloroben...

  • Article
  • Open Access
17 Citations
4,616 Views
21 Pages

Atopic dermatitis (AD) is a chronic inflammatory skin disease that may be related to gut microbes. Schizonepeta Tenuifolia Briquet (STB) and Alpinia Oxyphylla Miquel (AOM) has traditionally been used for anti-inflammatory activity. We evaluated the e...

  • Article
  • Open Access
1,123 Views
13 Pages

Deep Sea Minerals Ameliorate Dermatophagoides Farinae- or 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-like Skin Lesions in NC/Nga Mice

  • Hyo Sang Kim,
  • Myeong Hwan Kim,
  • Byeong Yeob Jeon,
  • You Kyung Jang,
  • Jeong Ki Kim,
  • Hyun Keun Song and
  • Kilsoo Kim

Background: Chronic pruritus and inflammatory skin lesions, characterized by high recurrence, are hallmarks of atopic dermatitis (AD). Despite its increasing prevalence, the development of therapeutic agents for AD remains limited. This study aimed t...

  • Article
  • Open Access
7 Citations
4,275 Views
13 Pages

NCM 1921, a Mixture of Several Ingredients, Including Fatty Acids and Choline, Attenuates Atopic Dermatitis in 1-Chloro-2,4-Dinitrobenzene-Treated NC/Nga Mice

  • Young-Sil Lee,
  • Won-Kyung Yang,
  • Eun-Hee Jo,
  • Seung Ho Shin,
  • Young-Cheol Lee,
  • Min-Cheol Park and
  • Seung-Hyung Kim

7 January 2020

Atopic dermatitis (AD) is a chronic inflammatory skin disease in humans. In this study, we evaluated the effects of a mixture (NCM 1921) of omega-3 butter, omega-3 beef tallow oil, omega-3 lard oil, caprylic acid, lauric acid, choline, and Fe on AD i...

  • Article
  • Open Access
9 Citations
8,303 Views
13 Pages

A Herbal Formula, Atofreellage, Ameliorates Atopic Dermatitis-Like Skin Lesions in an NC/Nga Mouse Model

  • Won-Yong Kim,
  • Hyeong-Geug Kim,
  • Hye-Won Lee,
  • Jin-Seok Lee,
  • Hwi-Jin Im,
  • Hyo-Seon Kim,
  • Sung-Bae Lee and
  • Chang-Gue Son

25 December 2015

We evaluated the anti-atopic dermatitis (AD) effect of Atofreellage (AF), a herbal formula composed of 10 medicinal plants. AD was induced on the dorsal skin areas of NC/Nga mice (male, seven weeks old) by daily application of 2,4-dinitrochlorobenzen...

  • Article
  • Open Access
4 Citations
3,791 Views
24 Pages

26 April 2023

Atopic dermatitis is a chronic skin disease that affects millions of people all over the world. The objective of this study was to evaluate the inhibitory effects of the roots of Glycyrrhiza uralensis (GU) and Donkey Hide Gelatin (DHG) water extracts...

  • Article
  • Open Access
1 Citations
2,961 Views
14 Pages

19 October 2024

Atopic dermatitis (AD) is a chronic inflammatory skin disorder associated with significant morbidity, including pruritus, recurrent skin lesions, and immune dysregulation. This study aimed to investigate the antioxidative and anti-AD effects of pepti...