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Article

11 Citations

4,079 Views

17 Pages

Design Space Calculation and Continuous Improvement Considering a Noise Parameter: A Case Study of Ethanol Precipitation Process Optimization for Carthami Flos Extract

Yanni Tai,
Haibin Qu and
Xingchu Gong

Separations2021, 8(6), 74;https://doi.org/10.3390/separations8060074

24 May 2021

The optimization of process parameters in the pharmaceutical industry is often carried out according to the Quality by Design (QbD) concept. QbD also emphasizes that continuous improvement should be performed in life cycle management. Process paramet...

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Article

25 Citations

7,343 Views

20 Pages

Comparative Analysis of the Effects of Hydroxysafflor Yellow A and Anhydrosafflor Yellow B in Safflower Series of Herb Pairs Using Prep-HPLC and a Selective Knock-Out Approach

Cheng Qu,
Lin-Yan Wang,
Wen-Tao Jin,
Yu-Ping Tang,
Yi Jin,
Xu-Qin Shi,
Li-Li Shang,
Er-Xin Shang and
Jin-Ao Duan

Molecules2016, 21(11), 1480;https://doi.org/10.3390/molecules21111480

6 November 2016

The flower of Carthamus tinctorius L. (Carthami Flos, safflower), important in traditional Chinese medicine (TCM), is known for treating blood stasis, coronary heart disease, hypertension, and cerebrovascular disease in clinical and experimental stud...

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Article

11 Citations

4,646 Views

12 Pages

Evaluation of Toxicity, Bacteriostatic, Analgesic, Anti-Inflammatory, and Antipyretic Activities of Huangqin-Honghua-Pugongying-Jinyinhua Extract

Dongyang Ye,
Jing Sun and
Yinqian Li

Vet. Sci.2021, 8(12), 330;https://doi.org/10.3390/vetsci8120330

15 December 2021

The extensive use of antibiotics has caused the global spread of multidrug-resistant bacteria and genes, seriously reducing antibiotic efficacy and threatening animal and human health. As an alternative, traditional Chinese veterinary medicine (TCVM)...

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Article

19 Citations

6,006 Views

13 Pages

Pharmacokinetic Comparison of Seven Major Bio-Active Components in Normal and Blood Stasis Rats after Oral Administration of Herb Pair Danggui-Honghua by UPLC-TQ/MS

Yi Jin,
Yu-Ping Tang,
Zhen-Hua Zhu,
Er-Xin Shang,
Han-Qing Pang,
Xu-Qin Shi,
Yan-Yan Chen,
Jin Wang,
Xing Chang and
An Kang
+ 6 authors

Molecules2017, 22(10), 1746;https://doi.org/10.3390/molecules22101746

17 October 2017

The compatibility between Danggui (Angelicae Sinensis Radix) and Honghua (Carthami Flos) is a known herb pair, which could activate blood circulation and dissipate blood stasis effects. In this paper, we quantified seven main bio-active components (h...

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Article

3 Citations

6,045 Views

16 Pages

Traditional Chinese Medicine for Topical Treatment of Skeletal Muscle Injury

Wing-Sum Siu,
Hui Ma,
Wen Cheng,
Wai-Ting Shum and
Ping-Chung Leung

Pharmaceuticals2023, 16(8), 1144;https://doi.org/10.3390/ph16081144

12 August 2023

Muscle injuries are common musculoskeletal problems, but the pharmaceutical agent for muscle repair and healing is insufficient. Traditional Chinese Medicine (TCM) frequently uses topical treatments to treat muscle injuries, although scientific evide...

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Article

1,241 Views

15 Pages

Paeoniflorin Improves Stroke by Modulating the ESR1 Pathway: Data Mining and Validation Based on Network Approaches

Zhenshan Sun,
Junjie Peng,
Jiangbangrui Chu,
Zhengyi Wang,
Kefan Hu,
Zhanpeng Feng,
Mingfeng Zhou,
Xingqin Wang,
Songtao Qi and
Zhu Zhang
+ 1 author

Pharmaceuticals2025, 18(7), 933;https://doi.org/10.3390/ph18070933

20 June 2025

Aim of the study: Traditional Chinese herbs have a unique therapeutic effect on stroke and numerous successful clinical cases. However, these clinical cases are highly dispersed, creating challenges for translational research. This study employs a ne...

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