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MDPIMDPI

8 Results Found

  • Article
  • Open Access
6 Citations
3,124 Views
12 Pages
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In Vivo Prevalence of Beta-Amyloid Pathology and Alzheimer’s Disease Co-Pathology in Idiopathic Normal-Pressure Hydrocephalus—Association with Neuropsychological Features

  • Efstratios-Stylianos Pyrgelis,
  • George P. Paraskevas,
  • Vasilios C. Constantinides,
  • Fotini Boufidou,
  • Leonidas Stefanis and
  • Elisabeth Kapaki
Biomedicines2024, 12(8), 1898;https://doi.org/10.3390/biomedicines12081898

20 August 2024

Idiopathic normal-pressure hydrocephalus (iNPH) is a clinic-radiological neurological syndrome presenting with cognitive deficits, gait disturbances and urinary incontinence. It often coexists with Alzheimer’s disease (AD). Due to the reversibl...

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  • Open Access
3 Citations
4,872 Views
12 Pages
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Treatment of Canine Disc-Associated Cervical Spondylomyelopathy with a Cervical Distraction–Stabilization Technique (C-LOX Combined with LCP Plate) and Clinical Outcomes

  • Marco Tabbì,
  • Giuseppe Barillaro,
  • Claudia Dina Interlandi,
  • Simona Di Pietro,
  • Domenico Fugazzotto,
  • Giovanna Lucrezia Costa,
  • Nicola Maria Iannelli,
  • Daniele Macrì,
  • Vincenzo Ferrantelli and
  • Francesco Macrì
Animals2023, 13(16), 2549;https://doi.org/10.3390/ani13162549

8 August 2023

Canine disc-associated cervical spondylomyelopathy (DA-CSM) is a form of caudal CSM, characterized by the compression of the spinal cord and nerve roots due to an intervertebral disc protrusion. It is more frequent in large canine breeds. A variety o...

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  • Open Access
1,977 Views
14 Pages
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Exploratory Analysis of Cerebrospinal Fluid IL-6 and IL-17A Levels in Subcortical Small-Vessel Disease Compared to Alzheimer’s Disease: A Pilot Study

  • Georgios Liakakis,
  • Aigli G. Vakrakou,
  • Fotini Boufidou,
  • Vasilios Constantinides,
  • Georgios Velonakis,
  • George P. Paraskevas,
  • Leonidas Stefanis and
  • Elisabeth Kapaki
Diagnostics2025, 15(6), 669;https://doi.org/10.3390/diagnostics15060669

10 March 2025

Background/Objectives: Low-grade inflammation in the form of microglial activation may be involved in neurodegenerative and vascular dementias. Subcortical small-vessel disease (SSVD) is the main form of vascular dementia, associated with brain barri...

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  • Open Access
12 Citations
5,667 Views
12 Pages
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Callosal Angle Sub-Score of the Radscale in Patients with Idiopathic Normal Pressure Hydrocephalus Is Associated with Positive Tap Test Response

  • Efstratios-Stylianos Pyrgelis,
  • George P. Paraskevas,
  • Vasilios C. Constantinides,
  • Fotini Boufidou,
  • Georgios Velonakis,
  • Leonidas Stefanis and
  • Elisabeth Kapaki
J. Clin. Med.2022, 11(10), 2898;https://doi.org/10.3390/jcm11102898

20 May 2022

The aim of the present study was the implementation of the composite imaging “Radscale” in patients with idiopathic normal pressure hydrocephalus (iNPH) and the evaluation of its score, as well as absolute stroke volume and peak flow velo...

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  • Open Access
4 Citations
2,482 Views
17 Pages
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Intracluster Sulphur Dioxide Oxidation by Sodium Chlorite Anions: A Mass Spectrometric Study

  • Chiara Salvitti,
  • Federico Pepi,
  • Anna Troiani and
  • Giulia de Petris
Molecules2021, 26(23), 7114;https://doi.org/10.3390/molecules26237114

24 November 2021

The reactivity of [NaL·ClO2]− cluster anions (L = ClOx−; x = 0–3) with sulphur dioxide has been investigated in the gas phase by ion–molecule reaction experiments (IMR) performed in an in-house modified Ion Trap mass sp...

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  • Open Access
1 Citations
1,652 Views
20 Pages
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Transcriptomic Analysis Reveals the Mechanism of MtLOX24 in Response to Methyl Jasmonate Stress in Medicago truncatula

  • Lei Xu,
  • Yanchao Xu,
  • Huanhuan Lv,
  • Yanran Xu,
  • Jiangqi Wen,
  • Mingna Li,
  • Junmei Kang,
  • Zhipeng Liu,
  • Qingchuan Yang and
  • Ruicai Long
Agriculture2024, 14(7), 1076;https://doi.org/10.3390/agriculture14071076

4 July 2024

Lipoxygenase (LOX) is associated with responses to plant hormones, environmental stresses, and signaling substances. Methyl jasmonate (MeJA) treatment triggers the production of LOX, polyphenol oxidase, and protease inhibitors in various plants, prod...

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  • Open Access
14 Citations
5,798 Views
18 Pages
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Mitochondrial Oxidative Stress and Mitophagy Activation Contribute to TNF-Dependent Impairment of Myogenesis

  • Daniil A. Chernyavskij,
  • Olga Yu. Pletjushkina,
  • Anastasia V. Kashtanova,
  • Ivan I. Galkin,
  • Anna Karpukhina,
  • Boris V. Chernyak,
  • Yegor S. Vassetzky and
  • Ekaterina N. Popova
Antioxidants2023, 12(3), 602;https://doi.org/10.3390/antiox12030602

1 March 2023

Many muscular pathologies are associated with oxidative stress and elevated levels of the tumor necrosis factor (TNF) that cause muscle protein catabolism and impair myogenesis. Myogenesis defects caused by TNF are mediated in part by reactive oxygen...

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  • Open Access
6 Citations
2,463 Views
11 Pages
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Alzheimer’s Disease CSF Biomarkers as Possible Indicators of Tap-Test Response in Idiopathic Normal Pressure Hydrocephalus

  • Efstratios-Stylianos Pyrgelis,
  • George P. Paraskevas,
  • Vasilios C. Constantinides,
  • Fotini Boufidou,
  • Myrto Papaioannou,
  • Leonidas Stefanis and
  • Elisabeth Kapaki
Brain Sci.2023, 13(11), 1593;https://doi.org/10.3390/brainsci13111593

15 November 2023

The aim of the present study is the evaluation of established Alzheimer’s disease (AD) cerebrospinal fluid (CSF) biomarkers in patients with idiopathic normal-pressure hydrocephalus (iNPH), both individually and as a total profile, and the inve...

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