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Article

3 Citations

1,847 Views

16 Pages

Benzyl Benzoate Isolation from Acridocarpus smeathmannii (DC.) Guill. & Perr Roots and Its Bioactivity on Human Prostate Smooth Muscle Contractions

Oluwafemi Ezekiel Kale,
Iskander Rauanov,
Claudia Huber,
Alexander Tamalunas,
Christian G. Stief,
Wolfgang Eisenreich and
Martin Hennenberg

Pharmaceuticals2025, 18(5), 687;https://doi.org/10.3390/ph18050687

6 May 2025

Background/Objectives: This study is the first report on isolating a natural benzyl benzoate (nBB) from Acridocarpus smeathmannii (DC.) Guill. & Perr roots. Methods: The structure was verified using GC-MS, HPLC-UV-VIS, and two-dimensional NMR. Si...

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Article

538 Views

17 Pages

A Bioactive Benzyl Terpene from Acridocarpus smeathmannii Inhibits Human Prostate Smooth Muscle Contractility

Oluwafemi Ezekiel Kale,
Claudia Huber,
Denis Schuldeis,
Alexander Tamalunas,
Martin Hennenberg and
Wolfgang Eisenreich

Molecules2026, 31(9), 1380;https://doi.org/10.3390/molecules31091380

22 April 2026

The roots of Acridocarpus smeathmannii were identified as a natural source of the benzyl-terpene 2-(5-isopropyl-4-methoxy-2-methylbenzyl)phenol (FAH-01, chamanen), which was isolated and structurally characterized by chromatographic and spectroscopic...

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