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  • Article
  • Open Access
54 Citations
12,372 Views
19 Pages

Development of a Single Vial Kit Solution for Radiolabeling of 68Ga-DKFZ-PSMA-11 and Its Performance in Prostate Cancer Patients

  • Thomas Ebenhan,
  • Mariza Vorster,
  • Biljana Marjanovic-Painter,
  • Judith Wagener and ,
  • Janine Suthiram,
  • Moshe Modiselle,
  • Brenda Mokaleng,
  • Jan Rijn Zeevaart and
  • Mike Sathekge
  • + 4 authors+ 0 author

14 August 2015

Prostate-specific membrane antigen (PSMA), a type II glycoprotein, is highly expressed in almost all prostate cancers. By playing such a universal role in the disease, PSMA provides a target for diagnostic imaging of prostate cancer using positron em...

(This article belongs to the Special Issue Preparation of Radiopharmaceuticals and Their Use in Drug Development)
  • Feature Paper
  • Review
  • Open Access
163 Citations
18,576 Views
12 Pages

For the positron emission tomography (PET) imaging of prostate cancer, radiotracers targeting the prostate-specific membrane antigen (PSMA) are nowadays used in clinical practice. Almost 10 years after its discovery, [68Ga]Ga-PSMA-11 has been approve...

(This article belongs to the Special Issue Targets, Tracers and Translation, Part 2 - New Horizons in Radiopharmaceutical Development)