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Design, Synthesis, Kinetic Analysis and Pharmacophore-Directed Discovery of 3-Ethylaniline Hybrid Imino-Thiazolidinone as Potential Inhibitor of Carbonic Anhydrase II: An Emerging Biological Target for Treatment of Cancer

  • Atteeque Ahmed,
  • Mubashir Aziz,
  • Syeda Abida Ejaz,
  • Pervaiz Ali Channar and ,
  • Aamer Saeed,
  • Seema Zargar,
  • Tanveer A. Wani,
  • Asad Hamad,
  • Qamar Abbas and
  • Song Ja Kim
  • + 6 authors+ 1 author
Biomolecules2022, 12(11), 1696;https://doi.org/10.3390/biom12111696

16 November 2022

Carbonic anhydrases (CA), having Zn2+ metal atoms, are responsible for the catalysis of CO2 and water to bicarbonate and protons. Any abnormality in the functioning of these enzymes may lead to morbidities such as glaucoma and different types of canc...

(This article belongs to the Special Issue Redox Regulation of Protein Functioning)
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