Cardiogenetics | Aims and Scope Update

Aims (old version):

Aims (new version):

Cardiogenetics (ISSN 2035-8148) is an international, peer-reviewed, open access journal which provides an advanced forum for studies related to all aspects of cardiogenetics (clinical, molecular, cellular, pharmacological). Cardiogenetics focuses on publishing reviews, regular research papers, communications, and case reports.

Cardiogenetics (ISSN 2035-8148) is an international, peer-reviewed, open access journal that provides an advanced forum for studies related to all aspects of cardiogenetics (clinical, molecular, cellular, pharmacological). Cardiogenetics focuses on publishing reviews, regular research papers, communications, and case reports, but other article types will also be considered. Submissions should focus on the intersection of cardiovascular medicine and genetics. There are no restrictions on the maximum length of papers. All research must provide sufficient methodological detail to ensure reproducibility of results.

Scope (old version):

Scope (new version):

As an essential resource to general physicians, cardiologists, and geneticists, Cardiogenetics’ primary purpose is to report original research in the following areas:

- Clinical and molecular aspects of inherited heart diseases: genotype–phenotype findings; follow-up data from inherited heart disease clinics; clinical findings from large and informative families with inherited heart diseases; studies on molecular imaging in inherited heart diseases.

- Clinical and molecular aspects of rare diseases: clinical imaging and molecular findings of rare diseases with cardiovascular involvement.

- Pharmacogenetics and pharmacogenomics: studies involving new drugs or well-known therapies in inherited heart diseases, rare diseases, and cardiovascular medicine; genetic/genomic profile and response to therapies.

- Stem cell studies: clinical trials and experimental studies involving cell studies/cell therapy.

- Diagnostic methods, including sequencing studies.

- Bioinformatics and statistical methods in genetics.

- Personalized medicine and therapies (gene therapy and gene editing).

- Molecular biology and pathophysiology of genetic and genomic diseases: biology of cells; pathways and systems; epigenetics and gene regulation; biology and pathophysiology of specific genes and non-coding DNA.

- Polygenic/multifactorial disorders.

- Cellular electrophysiological studies related to inherited arrhythmogenic conditions.

- Imaging in cardiogenetics.

- Mutation reports.

A space will be given to negative studies in cardiogenetics: this space will be dedicated to clinical, molecular, cellular, and pharmacological studies with a solid scientific background that lead to negative results.

As an essential resource to general physicians, cardiologists, and geneticists, Cardiogenetics’ primary purpose is to publish papers on the following topics:

- Clinical and molecular aspects of inherited heart diseases: genotype–phenotype findings; follow-up data from inherited heart disease clinics; clinical findings from large and informative families with inherited heart diseases; and studies on molecular imaging in inherited heart diseases.

- Clinical and molecular aspects of rare diseases with cardiovascular involvement: clinical imaging and molecular findings of rare genetic disorders that affect the heart and vasculature.

- Pharmacogenetics and pharmacogenomics in cardiovascular medicine: studies involving new drugs or well-known therapies in inherited heart diseases, rare diseases, and cardiovascular medicine; and genetic/genomic profile and response to therapies.

- Stem cells and regenerative therapies for genetic heart diseases: clinical trials and experimental studies involving cell studies/cell therapy, including gene editing in stem cells for cardiac repair.

- Diagnostic methods for cardiogenetic disorders: including but not limited to next-generation sequencing, comparative microarray analysis (CMA), optical genome mapping (OGM), and other techniques for the interrogation of genomic variants and events, variant interpretation, functional assays, and non-invasive imaging techniques specifically applied to inherited heart conditions.

- Bioinformatics and statistical genetics in heart disease: methods for analyzing cardiogenetic data, polygenic risk scores for cardiovascular traits, and computational approaches to identify heart disease-associated variants.

- Personalized medicine and gene-targeted therapies: gene therapy, antisense oligonucleotides, and gene editing (e.g., CRISPR) for inherited cardiovascular diseases.

- Molecular biology and pathophysiology of genetic and genomic cardiovascular diseases: biology of cells; pathways and systems; epigenetics and gene regulation; and biology and pathophysiology of specific genes and non-coding DNA.

- Polygenic/multifactorial cardiovascular disorders.

- Cellular electrophysiological studies related to inherited arrhythmogenic conditions.

- Cardiovascular imaging in the context of genetic disease.

- Mutation reports: descriptions of novel or potentially pathogenic variants in genes associated with cardiovascular phenotypes, with supporting family or functional data.

A space will be given to negative studies in cardiogenetics: this space will be dedicated to clinical, molecular, cellular, and pharmacological studies with a solid scientific background that lead to negative results.