Molecules | Selected Feature Papers in 2025 in the “Medicinal Chemistry” Section

1. “Chitosan Micro/Nanocapsules in Action: Linking Design, Production, and Therapeutic Application”
by Yaride Pérez-Pacheco, Bartosz Tylkowski and Ricard García-Valls
Molecules 2025, 30(2), 252; https://doi.org/10.3390/molecules30020252
Available online: https://www.mdpi.com/1420-3049/30/2/252

2. “Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase-B for the Treatment of Alzheimer’s Disease”
by Ayesha Asim, Michał K. Jastrzębski and Agnieszka A. Kaczor
Molecules 2025, 30(14), 2975; https://doi.org/10.3390/molecules30142975
Available online: https://www.mdpi.com/1420-3049/30/14/2975

3. “Microbiota-Derived Tryptophan Metabolite Indole-3-Propionic Acid-Emerging Role in Neuroprotection”
by Maja Owe-Larsson, Dominik Drobek, Paulina Iwaniak, Renata Kloc, Ewa M. Urbanska and Mirosława Chwil
Molecules 2025, 30(17), 3628; https://doi.org/10.3390/molecules30173628
Available online: https://www.mdpi.com/1420-3049/30/17/3628

4. “Vitamin K Properties in Stroke and Alzheimer’s Disease: A Janus Bifrons in Protection and Prevention”
by Lorenzo Grimaldi, Rosaria A. Cavallaro, Domenico De Angelis, Andrea Fuso and Giulia Sancesario
Molecules 2025, 30(5), 1027; https://doi.org/10.3390/molecules30051027
Available online: https://www.mdpi.com/1420-3049/30/5/1027

5. “Antifungal and Antioxidant Activity of Thiourea Derivatives Against Nosocomial Candida auris Strains Isolated in Romania”
by Marina Ionela Nedea (Ilie), Carmellina Daniela Bădiceanu, Irina Gheorghe-Barbu, Ioana Cristina Marinaș, Radu Pericleanu, Rareș-Ionuț Dragomir, Andreea Ștefania Dumbravă, Ana Maria Dascălu, Dragoș Șerban, Corneliu Tudor et al.
Molecules 2025, 30(8), 1675; https://doi.org/10.3390/molecules30081675
Available online: https://www.mdpi.com/1420-3049/30/8/1675

6. “Focus on PD-1/PD-L1-Targeting Antibodies in Colorectal Cancer: Are There Options Beyond Dostarlimab, Nivolumab, and Pembrolizumab? A Comprehensive Review”
by Mateusz Kciuk, Katarzyna Wanke, Weronika Kruczkowska, Beata Marciniak and Renata Kontek
Molecules 2025, 30(13), 2686; https://doi.org/10.3390/molecules30132686
Available online: https://www.mdpi.com/1420-3049/30/13/2686

7. “Doxorubicin Toxicity and Recent Approaches to Alleviating Its Adverse Effects with Focus on Oxidative Stress”
by Lyubomira Radeva and Krassimira Yoncheva
Molecules 2025, 30(15), 3311; https://doi.org/10.3390/molecules30153311
Available online: https://www.mdpi.com/1420-3049/30/15/3311

8. “Development of Vancomycin, a Glycopeptide Antibiotic, in a Suitable Nanoform for Oral Delivery”
by Ali A. Amer, Lewis Bingle, Cheng Shu Chaw and Amal Ali Elkordy
Molecules 2025, 30(7), 1624; https://doi.org/10.3390/molecules30071624
Available online: https://www.mdpi.com/1420-3049/30/7/1624

9. “Targeting Ocular Biofilms with Plant-Derived Antimicrobials in the Era of Antibiotic Resistance”
by Monika Dzięgielewska, Michał Tomczyk, Adrian Wiater, Aleksandra Woytoń and Adam Junka
Molecules 2025, 30(13), 2863; https://doi.org/10.3390/molecules30132863
Available online: https://www.mdpi.com/1420-3049/30/13/2863

10. “Flavonoids and Furanocoumarins Involved in Drug Interactions”
by Sabine Berteina-Raboin
Molecules 2025, 30(8), 1676; https://doi.org/10.3390/molecules30081676
Available online: https://www.mdpi.com/1420-3049/30/8/1676

11. “Recent Advances in Microtubule Targeting Agents for Cancer Therapy”
by Henrique C. Assunção, Patrícia M. A. Silva, Hassan Bousbaa and Honorina Cidade
Molecules 2025, 30(16), 3314; https://doi.org/10.3390/molecules30163314
Available online: https://www.mdpi.com/1420-3049/30/16/3314

12. “Spectroscopic Characterization Using ¹H and ¹³C Nuclear Magnetic Resonance and Computational Analysis of the Complex of Donepezil with 2,6-Methyl-β-Cyclodextrin and Hydroxy Propyl Methyl Cellulose”
by Nikoletta Zoupanou, Paraskevi Papakyriakopoulou, Nikitas Georgiou, Antigoni Cheilari, Uroš Javornik, Peter Podbevsek, Demeter Tzeli, Georgia Valsami and Thomas Mavromoustakos
Molecules 2025, 30(5), 1169;  https://doi.org/10.3390/molecules30051169
Available online: https://www.mdpi.com/1420-3049/30/5/1169

13. “Progress in Gliotoxin Research”
by Longqi Li, Yuxiu Liu, Qingmin Wang and Hongjian Song
Molecules 2025, 30(18), 3665; https://doi.org/10.3390/molecules30183665
Available online: https://www.mdpi.com/1420-3049/30/18/3665