Biomedicines Webinar | Non-Coding RNAs (ncRNAs) in Cancer, 2 September 2025
Non-coding RNAs comprise several categories, such as ribosomal and transfer RNAs, small nuclear and nucleolar RNAs, microRNAs, long non-coding RNAs, circular RNAs, etc. microRNAs (miRNAs) are single-stranded, small non-coding RNA molecules that epigenetically regulate gene expression, mostly through binding to the 3′-untranslated region (3′-UTR) of targeted messenger RNA (mRNA) molecules. Hence, they can mediate translational repression, usually combined with or followed by mRNA degradation. The human genome can produce more than a thousand different miRNAs, which regulate approximately 70% of protein-coding genes, thereby controlling the activity and function of key signaling pathways and cellular processes. These include cell proliferation, apoptosis, cell differentiation, and response to hypoxia. Additionally, miRNAs can function either as oncogenes or tumor suppressors. However, during the last decade, it has emerged that mutations and the dysregulation of long non-coding RNA (lncRNA) expression may significantly contribute to numerous human diseases. Alterations in the primary structure, secondary structure, and expression levels of lncRNAs and their cognate RNA-binding proteins (RBPs) have been shown to underlie the pathobiology of cancer, neurodegenerative and cardiovascular diseases. As recent studies have suggested, the involvement of lncRNAs in human diseases could be far more prevalent than previously thought. From a clinical perspective, some miRNAs and lncRNAs can also serve as molecular biomarkers and therapeutic targets for several human diseases.
This webinar will focus on the role of non-coding RNAs in cancer biology and their clinical applications as molecular cancer biomarkers, with an emphasis on miRNAs and lncRNAs.
Date: 2 September 2025 at 3:00 p.m. CEST | 9:00 a.m. EDT
Webinar ID: 853 2133 1321
Website: https://sciforum.net/event/Biomedicines-17
Register now for free!
| Speaker/Presentation | Time in CEST | Time in EDT |
| Dr. Christos K. Kontos Chair Introduction | 3:00–3:10 p.m. | 9:00–9:10 a.m. |
| Prof. Dr. Ioana Berindan-Neagoe Beyond the Genome: Non-Coding RNAs as Regulators in Cancer | 3:10–3:30 p.m. | 9:10–9:30 a.m. |
| Dr. Mona Batish Extracellular Transport of Non-Coding RNAs: Excellent Biomarkers for Cancer Diagnosis | 3:30–3:50 p.m. | 9:30–9:50 a.m. |
| Dr. Margaritis Avgeris The Role of Non-Coding RNAs in Cancer Biology | 3:50–4:10 p.m. | 9:50–10:10 a.m. |
| Dr. Nikolay Mehterov Diagnostic and Prognostic Value of MicroRNAs in Head and Neck and Thyroid Cancers | 4:10–4:30 p.m. | 10:10–10:30 a.m. |
| Dr. Sotirios G. Papageorgiou MicroRNAs in non-Hodgkin Lymphomas: Clinical Implications for Diagnosis and Prognosis | 4:30–4:50 p.m. | 10:30–10:50 a.m. |
| Q&A Session | 4:50–5:05 p.m. | 10:50–11:05 a.m. |
| Dr. Christos K. Kontos Closing of Webinar | 5:05–5:10 p.m. | 11:05–11:10 a.m. |
After registering, you will receive a confirmation email outlining how to join this webinar. Registrations with academic institutional email addresses will be prioritized.
Unable to attend? Register anyway, and we will let you know when the recording is available to watch.
Webinar Chairs and Keynote Speakers:
- Dr. Christos K. Kontos, Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece;
- Prof. Dr. Ioana Berindan-Neagoe, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania;
- Dr. Mona Batish, Department of Biological Sciences, University of Delaware, Delaware, DE, U.S.A.;
- Dr. Margaritis Avgeris, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece;
- Dr. Nikolay Mehterov, Department of Medical Biology, Medical University of Plovdiv, Plovdiv, Bulgaria;
- Dr. Sotirios G. Papageorgiou, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Relevant Topical Collection:
Collection Editor: Dr. Christos K. Kontos