Cutting-Edge Cancer Vaccines Enhanced by Nanotechnology

Dear Colleagues,

Cancer immunotherapies have significantly extended the survival time of cancer patients, revolutionized cancer treatment and opened a new era of cancer treatment. In cancer immunotherapy, cancer vaccines are among the most promising strategies, owing to their ability to educate the body’s immune system to recognize, target and remove tumor cells. Recently, the successful development of COVID-19 mRNA vaccines and dramatic advances in nanotechnologies have led to significant progress in developing cancer vaccines. In particular, nanotechnology can protect the delivery of antigens, enable sustained and efficient antigen delivery to specific targets, enhance immunogenicity and induce specific immune responses. Therefore, nanotechnology has played an indispensable role in the success of various clinical and preclinical vaccines.

In this Special Issue, original research articles and reviews related to the recent advances, current challenges and future perspectives in cutting-edge nanotechnology-based cancer vaccines are welcome. Research areas may include the following:

1. Nanoscale synthesis, structural regulation and functional design of polymers, lipids, inorganic particles and bio-derived materials for cancer vaccines;
2. Nano-vaccine adjuvants for therapeutic, prophylactic and in situ cancer vaccines;
3. Nanotechnology-based cancer vaccines combined with other cancer therapies, such as immune checkpoint inhibitors;
4. Mechanisms, safety and efficacy of nanotechnology-enhanced cancer vaccines.

I look forward to receiving your contributions.

Dr. Xiupeng Wang
Guest Editor

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