Antibodies in Autoimmune, Chronic, and Infectious Diseases: Pathogenic Mechanisms, Biomarkers, and Vaccine Development

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines, Clinical Advancement, and Associated Immunology".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 799

Special Issue Editors


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Guest Editor
Instituto de Investigación en Ciencias Biomédicas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Mexico
Interests: autoimmune diseases; antibody biomarkers; immunogenetics; inflammation; cytokines; B cell immunity; vaccines; chronic inflammatory diseases

E-Mail Website
Guest Editor
Instituto de Investigación en Ciencias Biomédicas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Mexico
Interests: cancer immunology; tumor microenvironment; antibody-based therapies; cytokines and inflammation; cellular immunotherapy; immunopathology; monoclonal and bispecific antibodies

E-Mail Website
Guest Editor
Instituto de Investigación en Ciencias Biomédicas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Mexico
Interests: autoimmune diseases; immunogenetics; inflammatory markers; antibody responses; cytokine networks; chronic inflammatory conditions; clinical immunology; diagnostic biomarkers; nutrition

Special Issue Information

Dear Colleagues,

Antibodies are central players in the immune system, acting as both sentinels and effectors in a wide range of physiological and pathological processes. In autoimmune diseases, antibodies often lose their specificity for foreign antigens and instead target self-components, contributing to chronic inflammation and tissue damage. In chronic conditions, antibodies may serve as biomarkers or modulators of disease progression, while in infectious diseases they are key components of both natural and vaccine-induced immunity.

The growing understanding of antibody diversity, functionality, and regulation has opened new avenues for diagnostic, prognostic, and therapeutic innovations. Moreover, the development of monoclonal antibodies, bispecific constructs, and antibody-based vaccines offers promising strategies for managing diseases that were previously difficult to treat.

This Special Issue aims to gather original research articles and comprehensive reviews that explore the roles of antibodies in autoimmune, chronic, and infectious diseases. We especially welcome contributions focused on antibody mechanisms, engineering, clinical applications, immune evasion strategies by pathogens, and novel approaches to antibody-based vaccine development.

We look forward to your valuable contributions.

Dr. Jorge Hernández-Bello
Dr. Mariel García Chagollán
Dr. Francisco Javier Turrubiates Hernández
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • autoantibodies
  • monoclonal antibodies
  • chronic diseases
  • infectious diseases
  • autoimmune diseases
  • antibody-based vaccines
  • immunotherapy
  • antibody biomarkers
  • b cell response
  • translational immunology

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Published Papers

This special issue is now open for submission.
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