Role of Host Pathogen Interactions and/or Epigenetics in Vaccine Development
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Pathogens-host Immune Interface".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 7657
Special Issue Editors
Interests: host-pathogen interactions; epigenetics; HMG proteins; vaccines; autophagy; nuclear receptors; autoimmunity; metabolic diseases
Interests: Mucosal Immunology; Host pathogen interactions; Therapeutic vaccines; Autoimmunity and Cancer immunology
Interests: Infectious Diseases; Infection and Immunity; Immunology; Vaccine; Host-Pathogen crosstalk; Tuberculosis; Transcriptomics
Special Issue Information
Dear Colleagues,
Globally vaccines administration saved millions of lives till now against infectious pathogens by inducing both hosts innate and acquired immunity. Enormous research efforts are being performed worldwide to improve currently used and newly developed candidate vaccine by intervening new strategies. Different types pathogens such as bacteria, viruses, fungi, protozoa and worms have evolved mechanism to escape the hostile host immune defense to cause infection. Hence, understanding host-pathogen interactions, and immune evasion mechanisms are key to improve the vaccine strategies and development. Interestingly, growing evidences suggest that vaccines and infections can alter the host epigenome and modulate immune responses. Initial evidences on alteration in DNA methylation induced by carcinogenetic viruses and bacteria highlight the interesting link between host-pathogen interactions and epigenetics. The universally administered BCG vaccine induces genome wide epigenetic reprogramming in innate immune cells which develops immune memory to confer heterologous protection against infections. This special issue of MDPI Vaccines brings together peer review articles and reviews on research that are focused on host-pathogen interactions and/ or Epigenetics in Vaccine development. We encourage submitting articles and review current efforts on vaccine development against all types of pathogens including that caused recent epidemics such as Ebola, MERS-CoV and SARS-coV-2 etc.Names
Dr. Ravikanth Nanduri
Dr. Bhagyaraj Ella
Dr. Hedwin Kitdorlang Dkhar
Guest Editors
Manuscript Submission Information
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Keywords
- Vaccine development
- Host-pathogen interactions
- Vaccine-Host interactions
- Epigenetics in vaccine development
- Vaccine induced epigenetics in host
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