Next-Generation Platforms for Vaccine Design and Immune Evaluation
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccine Design, Development, and Delivery".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 1638
Special Issue Editors
Interests: vaccine design; mRNA vaccines; computational modeling; bioinformatics
Interests: vaccine design; computational modeling; bioinformatics; systems immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The rapid development of new vaccine technologies, particularly during the COVID-19 pandemic, has underscored the transformative potential of innovative platforms in global health. Among these, mRNA-based vaccines, viral vectors, peptide and multi-epitope constructs, and nanoparticle delivery systems have opened new avenues for rational vaccine design and accelerated development timelines. At the same time, computational modeling, bioinformatics pipelines, and artificial intelligence tools are increasingly being integrated into the vaccine discovery process, enabling more accurate epitope prediction, optimization of antigen design, and in silico simulations of immune responses.
Despite these advances, several challenges remain, including the need to improve immunogenicity, ensure long-term protection, and understand the complexity of host–pathogen interactions. The integration of innovative vaccine platforms with comprehensive immunological evaluation—ranging from in silico models and omics-driven profiling to experimental and clinical validation—offers an unprecedented opportunity to address these gaps.
To achieve a more extensive understanding of recent scientific knowledge and current trends in this field, this Special Issue will focus on recent progress in novel vaccine platforms and immunological evaluation strategies. Based on your expertise and research, we invite you to contribute original research articles, reviews, or short communications, covering (i) the design and optimization of next-generation vaccines, (ii) computational and AI-driven approaches for vaccine development, (iii) nanoparticle and delivery technologies, (iv) systems immunology and omics-based evaluation of vaccine responses, and (v) translational and clinical perspectives in vaccine innovation.
Dr. Valentina Di Salvatore
Dr. Giulia Russo
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- vaccine design
- mRNA vaccines
- computational modeling
- immunoinformatics
- systems immunology
- nanoparticle-based delivery
- immunological evaluation
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