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Advances in the Control and Elimination of Parasitic Neglected Tropical...
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Advances in the Control and Elimination of Parasitic Neglected Tropical Diseases

A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Infectious Diseases".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 2167

Special Issue Editor

Dr. Hammed O. Mogaji

E-Mail Website
Guest Editor
Public Health Program, Department of Behavioral and Applied Social Sciences, Marian University, Indianapolis, IN, USA
Interests: helminth infections; neglected tropical diseases; schistosomiasis; lymphatic filariasis; onchocerciasis, trachoma; implementation science; epidemiology

Special Issue Information

Dear Colleagues,

Parasitic Neglected Tropical Diseases (NTDs) continue to affect the world’s most vulnerable populations, perpetuating poverty and limiting socioeconomic development. The first WHO NTD Road Map (2012–2020) galvanized global action, stimulating unprecedented commitments from pharmaceutical companies, philanthropists, and non-profit organizations, resulting in massive praziquantel donations for schistosomiasis control. By 2020, these commitments led to 600 million fewer people requiring interventions and 42 countries eliminating at least one NTD. Despite this progress, several targets remained unmet, underscoring the need for a paradigm shift from vertical, disease-specific programs toward integrated, country-owned, and cross-cutting strategies. The new WHO NTD Road Map (2021–2030) promotes three key shifts: enhancing accountability through impact-based indicators, mainstreaming NTD programs into national health systems, and fostering people-centered, multi-sectoral approaches. This Special Issue, “Advances in the Control and Elimination of Parasitic Neglected Tropical Diseases”, aims to highlight recent progress and innovations toward NTD control and elimination in the context of the 2030 Road Map. We invite contributions presenting original research, reviews, implementation experiences, impact assessments, and mixed-method studies from endemic countries that advance understanding of disease transmission, vector ecology, intervention coverage, bottlenecks, and programmatic success.

Dr. Hammed O. Mogaji
Guest Editor

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tropical Medicine and Infectious Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • parasites
  • parasite-host interaction
  • Chagas disease
  • echinococcosis
  • human African trypanosomiasis
  • leishmaniasis
  • onchocerciasis
  • lymphatic filariasis
  • schistosomiasis
  • soil-transmitted helminthiases
  • diagnosis and treatment
  • preventive chemotherapy
  • mass drug administration
  • prevention, control and elimination
  • monitoring and evaluation
  • impact assessment
  • morbidity management and prevention
  • vector control
  • environmental modification
  • One Health

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Published Papers (2 papers)

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Research

14 pages, 1269 KB  
Article
Schistosomiasis in Saudi Arabia (2002–2024): A National Analysis of Trends, Regional Heterogeneity, and Progress Toward Elimination
by Yasir Alruwaili
Trop. Med. Infect. Dis. 2026, 11(1), 25; https://doi.org/10.3390/tropicalmed11010025 - 16 Jan 2026
Viewed by 530
Abstract
Schistosomiasis remains a major neglected tropical disease globally and presents particular challenges for countries transitioning from control to elimination. Saudi Arabia represents a unique epidemiological setting, having shifted from historical endemic transmission to very low reported incidence, yet long-term national analyses remain limited. [...] Read more.
Schistosomiasis remains a major neglected tropical disease globally and presents particular challenges for countries transitioning from control to elimination. Saudi Arabia represents a unique epidemiological setting, having shifted from historical endemic transmission to very low reported incidence, yet long-term national analyses remain limited. A retrospective longitudinal analysis of national schistosomiasis surveillance data from 2002 to 2024 was conducted to evaluate temporal trends, clinical subtypes, regional distribution, and demographic characteristics. Joinpoint regression was used to identify significant changes in temporal trends, and autoregressive integrated moving average (ARIMA) models were applied to forecast national and regional trajectories. National incidence declined markedly from 5.5 per 100,000 in 2002 to 0.12 per 100,000 in 2024, with a notable change around 2010, followed by sustained low-level incidence. Intestinal schistosomiasis accounted for most cases, with increasing concentration among adult non-Saudi males and near-elimination among children. Regionally, cases were confined to a limited number of western and southwestern regions, particularly Ta’if, Al Baha, Jazan, and Madinah. Forecasting analyses indicated continued low-level detection without evidence of national resurgence. These findings demonstrate a transition to an elimination-maintenance phase and highlight the need for sustained surveillance in historically endemic regions and mobile populations. Full article
(This article belongs to the Special Issue Advances in the Control and Elimination of Parasitic Neglected Tropical Diseases)
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11 pages, 992 KB  
Article
Updating the Endemicity Map of Soil-Transmitted Helminthiasis in Ten Local Government Areas of Ondo State, Southwestern Nigeria
by Uwem F. Ekpo, Jacob Solomon, Hammed O. Mogaji, Francisca O. Olamiju, Fajana Oyinlola, Ijeoma Achu, Olanike O. Oladipupo, Alice Y. Kehinde, Imaobong O. Umah, Fatai Oyediran, Moses Aderogba and Louise K. Makau-Barasa
Trop. Med. Infect. Dis. 2026, 11(1), 24; https://doi.org/10.3390/tropicalmed11010024 - 14 Jan 2026
Viewed by 727
Abstract
As Nigeria advances toward the elimination of soil-transmitted helminthiasis (STH), updated endemicity maps are essential for guiding programmatic decisions. A cross-sectional study was conducted to update the STH endemicity maps in ten local government areas (LGAs) of Ondo State from July to August [...] Read more.
As Nigeria advances toward the elimination of soil-transmitted helminthiasis (STH), updated endemicity maps are essential for guiding programmatic decisions. A cross-sectional study was conducted to update the STH endemicity maps in ten local government areas (LGAs) of Ondo State from July to August 2024. LGAs were stratified into three categories (C1–C3) based on the history of preventive chemotherapy (PC), with C1 being endemic LGAs with ≥5 effective rounds of PC, C2 being endemic LGAs with <5 effective rounds of PC, and C3 being low-endemicity (STH prevalence <20%; PC not required). A total of 4507 school-aged children (5–14 years) from 151 systematically selected communities (15 per LGA) provided fresh stool samples to assess the prevalence and intensity of STH. Stool samples were examined using the Kato-Katz technique. Prevalence of STH was aggregated at the LGA level and compared with World Health Organization thresholds. In the first category (C1), the baseline prevalence was reduced significantly by 60–96%, with specific prevalence in Akoko Southwest (from 28.2% to 0.4%, Risk Ratio (RR): 0.01), Akure North (from 39% to 1.5%, RR = 0.04), Ifedore (from 25% to 2.5%, RR = 0.10), and Ondo East (from 45.2% to 8.2%, RR = 0.18). In the second category (C2), the baseline was reduced significantly by 66–100%, with Akure South (from 29% to 1.2%, RR = 0.04), Ose (from 20% to 2.2%, RR = 0.11), Owo (~100% reduction), and Odigbo (38% to 12.8%, RR = 0.34). In the C3 LGAs, infection was significantly below the baseline threshold, with Akoko Northwest (5.2% to 0.9%, RR = 0.17) and Idanre (from 14.2% to 1.8%, RR = 0.13). Overall, significant reductions in STH prevalence were observed across the surveyed LGAs, with risk ratios ranging from 0.04 to 0.40. These findings updated the endemicity map for the ten LGAs in Ondo State, demonstrating significant progress toward STH elimination following PC implementation. Full article
(This article belongs to the Special Issue Advances in the Control and Elimination of Parasitic Neglected Tropical Diseases)
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