Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Toxin-Antitoxin System in Bacteria"
Deadline for manuscript submissions: closed (15 May 2016).
Toxin antitoxin (TA) systems are gaining more and more attendance as key modulators in bacterial lifestyle. Originally identified as plasmid maintenance systems, their function was considered to be exclusively to kill offspring devoid of the plasmid. More recently, TA systems were shown to be wide-spread in bacteria, and novel families of TA systems are continuously reported in the literature. These systems are not only found to be encoded on plasmids, but are also highly prevalent on the chromosomes of bacteria. A multitude of different functions have been attributed to TA systems, such as ranging from being selfish entities to systems that play major roles in bacterial persistence, biofilm formation, or virulence. Nevertheless, the current picture of TA system seems to be far from complete. Thus, there are constant discussions and sometimes revisions in the field and, as a matter of fact, conflicting hypotheses have been established in the past.
TA systems, however, are currently at a crossroad of research, and they are emerging as important factors that support bacteria, for instance, during stress conditions, in sustaining unfavorable conditions, or in pathogenicity. Important questions, such as: how are the expression and activation of TA systems regulated, what is the biological implication of their horizontal and lateral spread, why are there so many, and so forth, are still waiting to be answered for many systems? Thus, Toxins decided to launch a Special Issue on this topic to which you are invited to contribute your research.
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.