Cellular Toxicity of the Mycotoxins: From In Vitro Testing to Single Cell Analysis

Dear Colleagues,

Exposure to mycotoxins contaminating food and feed as well as indoor environments can cause serious adverse effects in humans and animals. Owing to variations in cell physiology, the toxicity of mycotoxins is highly dependent on the organs and, more specifically, the types of cell encountered. Precision toxicology, built upon isolation of small groups of cells or even single cells, is a new concept to probe subtle intracellular changes in response to xenobiotics. It is of great interest to assess the toxicity of mycotoxins. Cell culture testing as well as single cell analysis provide useful tools to determine the toxicity of mycotoxins, to delineate their mechanism of action, and to characterize target pathways. They can also be used to identify solutions to control or relieve the toxicological effects of these toxins. Moreover, these in vitro approaches can be valuable tools for the screening of interactive potential in the mycotoxin and/or conjugated form mixtures that humans and animals are exposed to.

This Special Issue of Toxins will present recent studies on the toxicity of mycotoxins on targeted human and animal cells, and the associated mechanisms. Therefore, papers dealing with new cellular or/and multicellular systems as well as mycotoxin interactions effects are welcome. Papers considering -omics or descriptive approaches to understand mechanisms are invited. Both research papers and review articles proposing novelties or overviews, respectively, are welcome.

Dr. Isabelle P. Oswald
Dr. Nolwenn Hymery
Dr. Imourana Alassane-Kpembi
Guest Editors

Manuscript Submission Information

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