Mycotoxin Health Exposure: Molecular Interactions and Cytotoxicity
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Mycotoxins".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 1687
Special Issue Editor
Interests: cell culture; flow cytometry; cell biology; immunology; macrophage; toxicology; dendritic cells; mycotoxins; monocytes; hepatocytes, intestinal cells; aflatoxin; cytotoxicity assays; acute toxicity; food contaminants; food toxicology; mycotoxin metabolites
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mycotoxins are secreted as low-molecular-weight secondary metabolites by a variety of fungi species. Mycotoxins mainly enter the food chain at the pre-harvest or post-harvest stage when harvested crops are stored in storerooms where conditions are conducive to fungal growth. The occurrence of mycotoxins is widespread, and the mycotoxin-induced contamination of food and feed is a global food safety problem. A large number of food/feed products and beverages are contaminated by mycotoxins, resulting in economic welfare losses. Most toxin-producing fungi can simultaneously generate various mycotoxins and result in the co-occurrence of multiple mycotoxins. Although over 300 to 400 compounds are now recognized as mycotoxins, only a few are toxic. Mycotoxins exhibit both acute and chronic toxic effects in humans and animals. Cytotoxicity is one of the most important adverse properties of mycotoxins. Moreover, the effects are caused by a combination of molecular mechanisms of action, involving a multitude of molecular targets and pleiotropic molecular toxicity. It is therefore essential to have relevant data to fill the research gap pertaining to mycotoxin mechanisms (both alone and mixtures). Omics approaches, like transciptomic, proteomic, and metabolomic approaches, are now readily employed as a key tool to elucidate biological pathways, molecular mechanisms, and the toxicity of mycotoxins (alone and in mixtures).
This Special Issue of Toxins on “Mycotoxin Health Exposure: Molecular Interactions and Cytotoxicity” aims to provide a comprehensive view of cytotoxicity and molecular mechanisms, as well as their influence on cellular homeostasis at the various 'omics' levels in order to explain mycotoxin toxicity.
Dr. Nolwenn Hymery
Guest Editor
Manuscript Submission Information
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Keywords
- mycotoxin interactions
- molecular target
- cytotoxicity
- mixture mycotoxins
