Special Issue "Animal Venoms and Pain"
Deadline for manuscript submissions: closed (15 October 2017).
Whether by an ant bite, scorpion sting, envenomation by a spitting cobra, or a brush with a sea anemone—animal venoms are well recognised for their devastating effects on sensory neurons. These effects cause incapacitating pain for the victim and enable a quick retreat for the perpetrator.
However, apart from the apparent survival advantage that inflicting pain on predators conveys, venoms have also evolved many components that, by virtue of their exquisite potency and specificity for key signalling molecules in the mammalian nervous system, exert potent analgesic effects.
This Special Issue of Toxins will cover recent developments relating to animal venoms and pain, including perspectives on the evolution, mechanism of action and structure-function of pro-algesic and analgesic venom components.
The individual articles will review
- The evolutionary processes shaping development of toxins targeting pain pathways
- Pharmacology of venom peptides targeting pain pathways, including toxins targeting transient receptor potential channels, G-protein coupled receptors and voltage-gated ion channels involved in pain.
- Insights into structure-activity of toxins acting at pain targets
- Snake venom components targeting peripheral sensory neurons
- Therapeutic applications of venoms for treatment of pain
Assoc. Prof. Stuart M. Brierley
Dr. Irina Vetter
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Transient receptor potential channels
- G-protein coupled receptors
- Voltage-gated ion channels