Isolation, Characterization and Toxicology of Ribosome-Inactivating Proteins and Lectins
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Plant Toxins".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 60
Special Issue Editors
Interests: lectins; toxicity; ribosome-inactivating proteins; proteins as drug targets
Special Issues, Collections and Topics in MDPI journals
2. Institute of Industrial Pharmacy, Complutense University of Madrid, E-28040 Madrid, Spain
Interests: excipient; vectorization; green technologies; lectin; glycobiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Methods for isolating toxins or proteins in plants are very important for characterizing some of the proteins synthesized by plants during their development. In this Special Issue, we will analyze proteins (RIPs) with polynucleotide: adenosine glycosylase activity, which halt protein production when ribosomal RNA is damaged. We will also analyze proteins (lectins) with the ability to bind to glycosidic residues. These proteins are known to protect plants against pathogens and opportunistic insects, helping the plant to respond to stress and prevent disease.
Environmental changes in plant development enable the presence of RIPs and lectins to ensure their natural defenses. It is interesting to consider their levels and amino acid modification to understand the metabolic mechanisms of plant cells in relation to climate change.
The presence of some lectins, such as phytohemagglutinin, is considered to be an antinutrient that poses challenges for food processing and human nutrition. However, others are well regarded in medicine.
In recent years, RIPs and lectins have been studied for their antitumor activity, and research into their use as immunomodulators is expanding. Therefore, the presence and role of RIPs and lectins in a changing environment requires further study, and their isolation is of great interest.
Prof. Dr. Maria Angeles Rojo
Prof. Dr. Damian Cordoba-Diaz
Guest Editors
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Keywords
- ribosome-inactivating proteins (RIPs)
- lectins
- toxicology
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