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Optofluidic Lasers for Biological Sensing

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 3567

Special Issue Editor


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Guest Editor
Department of Electrical Engineering, Chang Gung University, Taiwan
Interests: biomedical sensor chip design; mmWAVE chip design

Special Issue Information

Dear Colleagues,

In the past ten years, optofluidic lasers, a new type of laser material that uses biochemical or biological molecules in the gain medium, have emerged in the biomedical and biological field. The optofluidic laser has been quickly evaluated in bio-sensing, outperforming and complementing conventional fluorescence-based detection. When analyzing thermal dynamics of two DNA strands in many biomedical and biological applications, such as single nucleotide polymorphism (SNP) and oriented DNA sequence detection, to understand the DNA sequence, many genotyping methods have been proposed. However, the most important and distinguished method uses optofluidic lasers. The laser amplifies the small thermal dynamic difference between the target and the single-base-mismatched DNA, resulting in a differential signal, signal-to-noise ratio (SNR), that is orders of magnitude greater than with traditional fluorescence-based methods. Intracavity DNA detection using optofluidic devices enables rapid and easy analysis of DNAs with long sequences.

The Special Issues will focus on but is not limited to the following topics:

  1. Plasmonic nanocavity laser design.
  2. Photonic crystal based optofluidic laser design.
  3. Random lasers design.
  4. High Q-factor cavity design.
  5. Laser without excitation mechanism design.
  6. Pumping laser design.
  7. In vitro biomolecular analysis and applications.
  8. In live cells biological analysis.
  9. Biological analysis in tissues and potential applications

The Guest Editor encourages researchers from universities and medical-engineering communities to provide original data and papers. The Issue will accept high-quality original research results and review articles that will allow readers to learn more about technologies related to optofluidic lasers and other related topics.

Therefore, we invite you to submit articles covering advances in optofluidic lasers and their applications and test performance across different fields, as well as articles related to the listed topics.

Dr. Weicheng Lin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Optofluidic laser
  • cavity
  • excitation
  • biosensing
  • photonics
  • lab-on-a-chip

Published Papers (1 paper)

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15 pages, 2450 KiB  
Systematic Review
Systematic Review of Diagnostic Sensors for Intra-Abdominal Pressure Monitoring
by Chien-Hung Liao, Chi-Tung Cheng, Chih-Chi Chen, Yu-Hsin Wang, Hsin-Tzu Chiu, Cheng-Chun Peng, Uei-Ming Jow, Yen-Liang Lai, Ya-Chuan Chen and Dong-Ru Ho
Sensors 2021, 21(14), 4824; https://doi.org/10.3390/s21144824 - 15 Jul 2021
Cited by 4 | Viewed by 3251
Abstract
Intra-abdominal pressure (IAP) is defined as the steady-state pressure within the abdominal cavity. Elevated IAP has been implicated in many medical complications. This article reviews the current state-of-the-art in innovative sensors for the measurement of IAP. A systematic review was conducted on studies [...] Read more.
Intra-abdominal pressure (IAP) is defined as the steady-state pressure within the abdominal cavity. Elevated IAP has been implicated in many medical complications. This article reviews the current state-of-the-art in innovative sensors for the measurement of IAP. A systematic review was conducted on studies on the development and application of IAP sensors. Publications from 2010 to 2021 were identified by performing structured searches in databases, review articles, and major textbooks. Sixteen studies were eligible for the final systematic review. Of the 16 articles that describe the measurement of IAP, there were 5 in vitro studies (31.3%), 7 in vivo studies (43.7%), and 4 human trials (25.0%). In addition, with the advancement of wireless communication technology, an increasing number of wireless sensing systems have been developed. Among the studies in this review, five presented wireless sensing systems (31.3%) to monitor IAP. In this systematic review, we present recent developments in different types of intra-abdominal pressure sensors and discuss their inherent advantages due to their small size, remote monitoring, and multiplexing. Full article
(This article belongs to the Special Issue Optofluidic Lasers for Biological Sensing)
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