Optofluidic Lasers for Biological Sensing

Dear Colleagues,

In the past ten years, optofluidic lasers, a new type of laser material that uses biochemical or biological molecules in the gain medium, have emerged in the biomedical and biological field. The optofluidic laser has been quickly evaluated in bio-sensing, outperforming and complementing conventional fluorescence-based detection. When analyzing thermal dynamics of two DNA strands in many biomedical and biological applications, such as single nucleotide polymorphism (SNP) and oriented DNA sequence detection, to understand the DNA sequence, many genotyping methods have been proposed. However, the most important and distinguished method uses optofluidic lasers. The laser amplifies the small thermal dynamic difference between the target and the single-base-mismatched DNA, resulting in a differential signal, signal-to-noise ratio (SNR), that is orders of magnitude greater than with traditional fluorescence-based methods. Intracavity DNA detection using optofluidic devices enables rapid and easy analysis of DNAs with long sequences.

The Special Issues will focus on but is not limited to the following topics:

1. Plasmonic nanocavity laser design.
2. Photonic crystal based optofluidic laser design.
3. Random lasers design.
4. High Q-factor cavity design.
5. Laser without excitation mechanism design.
6. Pumping laser design.
7. In vitro biomolecular analysis and applications.
8. In live cells biological analysis.
9. Biological analysis in tissues and potential applications

The Guest Editor encourages researchers from universities and medical-engineering communities to provide original data and papers. The Issue will accept high-quality original research results and review articles that will allow readers to learn more about technologies related to optofluidic lasers and other related topics.

Therefore, we invite you to submit articles covering advances in optofluidic lasers and their applications and test performance across different fields, as well as articles related to the listed topics.

Dr. Weicheng Lin
Guest Editor

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