Special Issue "Aptasensors 2016"
Deadline for manuscript submissions: closed (15 February 2017) | Viewed by 25243
Interests: aptamer selection and characterization; SELEX; aptamer based sensors and assays; biosensor development and application; bioelectrotechnology; bioelectrochemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue in Sensors: Aptamers and Applications
Special Issue in Biosensors: Feature Papers: State-of-the-Art Biosensors Technology 2018
Special Issue in Sensors: Recent Advances and Emerging Applications of Aptamers
The last year was the 25th anniversary of the ‘aptamer’ termed functional biomacromolecules and of the in vitro selection and amplification technology (SELEX) used for their development. In 1990, Tuerk & Gold and Ellington & Szostak, independently described their discoveries to generate RNA aptamers able to bind a protein molecule (Science 249, 1990, 505–510) and synthetic organic dyes (Nature 346, 1990, 818–822), respectively. Aptamers are still very attractive functional molecules that are applied by researchers from different disciplines in areas such as nanotechnology, synthetic and chemical biology, analytics, clinical diagnostics, and therapy. The discovery of high-quality aptamers for relevant targets proceeds. The first commercial products based on aptamers are on the market, such as Macugen® (Pfizer Inc., US) as a therapeutic aptamer to treat wet macular degeneration; the ELISA-like assays for detection of Ochratoxin A and aflatoxin (NeoVentures Biotechnologies, Canada); and others. In addition to these applications, aptamers are in great demand in the development of new biosensors, the so-called aptasensors. The aptamers are used as sensitive and selective bio-receptors coupled with a variety of transducer principles, such as optical, mass-sensitive, and electrochemical detection. The analytes cover a wide range from small molecules, such as nucleotides, cofactors, amino acids, organic molecules over peptides, polysaccharides and proteins to complex structures such as whole cells, viruses, and single cell organisms. Aptasensors offer great potential to measure substances in clinical diagnostics, environmental analytics, food and biotechnology industries, process engineering, and others.
With this re-opening of the Special Issue, we invite you again to contribute with your full research papers and review articles showing the highly-dynamic evolvements in the field of aptasensor development. We look forward to and welcome your participation in this Special Issue.
Dr. Beate Strehlitz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- affinity sensor
- mass sensitive
- label- and label-free detection