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Open AccessArticle

One Step Assembly of Thin Films of Carbon Nanotubes on Screen Printed Interface for Electrochemical Aptasensing of Breast Cancer Biomarker

1
Interdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS Institute of Information Technology, Lahore 54000, Pakistan
2
BAE: Biocapteurs-Analyses-Environnement, Universite de Perpignan Via Domitia, 52 Avenue Paul Alduy, Perpignan Cedex 66860, France
3
Technological Chemistry Department, Federal University of Maranhão, CCET/UFMA, Av. Portugueses, Cidade Universitária do Canga, São Luis 65080-040, MA, Brazil
*
Authors to whom correspondence should be addressed.
Sensors 2016, 16(10), 1651; https://doi.org/10.3390/s16101651
Received: 17 August 2016 / Accepted: 29 September 2016 / Published: 6 October 2016
(This article belongs to the Special Issue Aptasensors 2016)
Thin films of organic moiety functionalized carbon nanotubes (CNTs) from a very well-dispersed aqueous solution were designed on a screen printed transducer surface through a single step directed assembly methodology. Very high density of CNTs was obtained on the screen printed electrode surface, with the formation of a thin and uniform layer on transducer substrate. Functionalized CNTs were characterized by X-ray diffraction spectroscopy (XRD), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA) and Brunauer–Emmett– Teller (BET) surface area analyzer methodologies, while CNT coated screen printed transducer platform was analyzed by scanning electron microscopy (SEM), atomic force microscopy (AFM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The proposed methodology makes use of a minimum amount of CNTs and toxic solvents, and is successfully demonstrated to form thin films over macroscopic areas of screen printed carbon transducer surface. The CNT coated screen printed transducer surface was integrated in the fabrication of electrochemical aptasensors for breast cancer biomarker analysis. This CNT coated platform can be applied to immobilize enzymes, antibodies and DNA in the construction of biosensor for a broad spectrum of applications. View Full-Text
Keywords: thin films; carbon nanotubes; high density; electrochemical aptasensor; cancer diagnosis thin films; carbon nanotubes; high density; electrochemical aptasensor; cancer diagnosis
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MDPI and ACS Style

Nawaz, M.A.H.; Rauf, S.; Catanante, G.; Nawaz, M.H.; Nunes, G.; Marty, J.L.; Hayat, A. One Step Assembly of Thin Films of Carbon Nanotubes on Screen Printed Interface for Electrochemical Aptasensing of Breast Cancer Biomarker. Sensors 2016, 16, 1651. https://doi.org/10.3390/s16101651

AMA Style

Nawaz MAH, Rauf S, Catanante G, Nawaz MH, Nunes G, Marty JL, Hayat A. One Step Assembly of Thin Films of Carbon Nanotubes on Screen Printed Interface for Electrochemical Aptasensing of Breast Cancer Biomarker. Sensors. 2016; 16(10):1651. https://doi.org/10.3390/s16101651

Chicago/Turabian Style

Nawaz, Muhammad A.H.; Rauf, Sajid; Catanante, Gaelle; Nawaz, Mian H.; Nunes, Gilvanda; Marty, Jean L.; Hayat, Akhtar. 2016. "One Step Assembly of Thin Films of Carbon Nanotubes on Screen Printed Interface for Electrochemical Aptasensing of Breast Cancer Biomarker" Sensors 16, no. 10: 1651. https://doi.org/10.3390/s16101651

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