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Special Issue "Advanced Biosensing of Natural Bioactive Compounds"

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 31 October 2020.

Special Issue Editors

Dr. Isabel Cristina Oliveira González Cunha
Website
Guest Editor
CIIMAR/Universidade do Porto, 4450-208 Matosinhos, Portugal
Interests: aquatic ecotoxicology; cyanobacteria; drug discovery; cell sensors; environmental monitoring; marine biotechnology; lipids metabolism; peroxisome proliferator-activated receptors (PPARs); bioactive compounds
Dr. Manuela Faria Frasco
Website
Guest Editor
BioMark Sensor Research/ ISEP (Instituto Superior de Engenharia do Porto), 4249-015 Porto, Portugal
Interests: nanobiotechnology; biosensors; bioinspired photonics; biomimetic imprinting; biomarkers; sustainable biomaterials; health and environmental monitoring
Prof. Dr. Maria Goreti Ferreira Sales
Website
Guest Editor
BioMark Sensor Research/ ISEP (Instituto Superior de Engenharia do Porto), 4249-015 Porto, Portugal
Interests: molecularly-imprinted polymers; antibodies; electrochemical detection; optical detection; biosensors
Prof. Dr. Vitor Manuel Oliveira Vasconcelos
Website
Guest Editor
Centro Interdisciplinar de Investigaco Marinha e Ambiental - CIIMAR/CIMAR-LA, Porto, Portugal
Interests: cyanobacteria; toxins; cyanotoxins; marine biotechnology; secondary metabolites; cyanobacterial blooms; ecotoxicology; environmental contamination
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Natural bioactive compounds and drug discovery are important research topics that have been receiving much attention. Live organisms produce countless compounds that result from their inumerous metabolic pathways. Bioactive compounds may have medical and pharmaceutical character by promoting health and healing and acting in specific pathways of the target organism but may also target deleterous organisms, acting in, for example, an anti-bacterial, anti-virus, anti-parasitic, anti-biofouling, anti-biofilm, and anti-bloom capacity by killing, weakening, or repelling them. Bioactive compounds also include those that cause harmful effects, as in the case of toxins.

Drug discovery and screening of bioactive compounds can be boosted by recent advances in biosensing technologies, benefiting particularly from the sensitivity and specificity demonstrated by advanced biosensor devices. These innovative analytical tools are getting progressively more cost-effective and portable, fulfilling the demands of the several stages of the drug discovery process. This Special Issue will highlight the progress in the design and use of biosensors for the following:

1) Detection, quantification, and concentration of bioactive natural compounds in the processes of drug discovery, including screening and high-throughput (HTP) screening of bioactivity in extracts and fractions of organisms;

2) Elucidation of the molecular mode of action of isolated compounds; and

3) Detection of bioative compounds in the environment, namely toxins and other relevant allellopatic compounds important to humans and to understanding ecological phenomena.

Such advanced biosensing technology covers the use of aptamers, antibodies, enzymes, cells, and even biomimetic methodologies, such as molecularly imprinted polymers (MIPs), using new nanobiomaterials with enhanced properties and including on-site sensing in real-time.

Dr. Isabel Cristina Oliveira González Cunha
Dr. Manuela Faria Frasco
Prof. Dr. Maria Goreti Ferreira Sales
Prof. Dr. Vitor Manuel Oliveira Vasconcelos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biosensors
  • Biosensor-based bioactivity screening assays
  • Drug discovery
  • Natural compounds
  • Bioactive compounds
  • Aptasensors
  • Molecularly imprinted polymers (MIPs)
  • Freshwater and marine toxins
  • Environmental toxin survillance
  • Electrochemical detection
  • Optical detection
  • Cell sensors

Published Papers

This special issue is now open for submission.
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