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Nanomaterial-Based Biochemical Sensors and Their Applications
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Nanomaterial-Based Biochemical Sensors and Their Applications

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Chemical Sensors".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 5697

Special Issue Editor

Dr. Meng Lin

E-Mail Website
Guest Editor
School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China
Interests: electrochemical (bio)sensors; nanomaterials synthesis and applications; electrocatalysis

Special Issue Information

Dear Colleagues,

Sensing analysis is an important method within analytical chemistry. Biochemical sensors are widely used in biological analysis, environmental monitoring, and other fields because of their high selectivity, high sensitivity, and high stability.

Due to remarkable achievements in nanotechnology and nanoscience, nanomaterials have become an important part of biochemical sensors. Biochemical sensors prepared using new nanomaterials show better performance in analysis and detection.

This Special Issue focuses on recent advances in chemical sensors and biosensors based on nanomaterials and nanostructures. It aims to provide the reader with a clear and concise view of new advances in areas ranging from the design and fabrication strategies to their applications.

Areas of particular interest for this Special Issue include, but are not limited to, the following:

  • Biosensors;
  • Chemical Sensors;
  • Fluorescent Sensors;
  • Electrochemical Sensors and Sensor arrays.

Dr. Meng Lin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensors
  • chemical sensors
  • fluorescent sensors
  • electrochemical sensors
  • electrochemistry
  • electronic tongue
  • electronic nose
  • environmental monitoring

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Research

11 pages, 2643 KiB  
Article
Gold–Mercury–Platinum Alloy for Light-Enhanced Electrochemical Detection of Hydrogen Peroxide
by Yunping Wei, Runze Li and Meng Lin
Sensors 2025, 25(1), 135; https://doi.org/10.3390/s25010135 - 29 Dec 2024
Cited by 1 | Viewed by 683
Abstract
In this study, a simple and easy synthesis strategy to realize the modification of AuHgPt nanoalloy materials on the surface of ITO glass at room temperature is presented. Gold nanoparticles as templates were obtained by electrochemical deposition, mercury was introduced as an intermediate [...] Read more.
In this study, a simple and easy synthesis strategy to realize the modification of AuHgPt nanoalloy materials on the surface of ITO glass at room temperature is presented. Gold nanoparticles as templates were obtained by electrochemical deposition, mercury was introduced as an intermediate to form an amalgam, and then a galvanic replacement reaction was utilized to successfully prepare gold–mercury–platinum (AuHgPt) nanoalloys. The obtained alloys were characterized by scanning electron microscopy, UV–Vis spectroscopy, X-ray photoelectron spectroscopy and X-ray diffraction techniques. The electrochemical sensing performance of the AuHgPt-modified electrode for hydrogen peroxide was evaluated by cyclic voltammetry and chronoamperometry. Under light conditions, the AuHgPt-modified electrode exhibited a desirable current response in the detection of hydrogen peroxide due to the synergistic effect of the localized surface plasmon resonance effect inherent in gold nanoparticles, and this synergistic effect improved the sensitivity of hydrogen peroxide detection. Meanwhile, the AuHgPt-modified electrode also exhibited better stability and reproducibility, which makes the modified electrode have great potential for various applications in the field of electrochemical sensing. Full article
(This article belongs to the Special Issue Nanomaterial-Based Biochemical Sensors and Their Applications)
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11 pages, 5999 KiB  
Article
Short-Peptide-Modified Copper Nanoclusters as a Fluorescent Probe for the Specific Detection of Ascorbic Acid
by Jiataiqi Li, Xin Lan and Xingcen Liu
Sensors 2024, 24(21), 6974; https://doi.org/10.3390/s24216974 - 30 Oct 2024
Viewed by 818
Abstract
Metal nanoclusters assembled using short peptides as templates exhibit significant potential for development and application in the fields of catalysis and biomedicine, owing to their distinctive electronic structure, favorable optical properties, and biocompatibility. Among them, tripeptides exhibit a simpler structure and greater flexibility, [...] Read more.
Metal nanoclusters assembled using short peptides as templates exhibit significant potential for development and application in the fields of catalysis and biomedicine, owing to their distinctive electronic structure, favorable optical properties, and biocompatibility. Among them, tripeptides exhibit a simpler structure and greater flexibility, enabling them to readily co-assemble with other functional components to create novel materials with significant application value. They can be assembled with copper ions to synthesize highly efficient luminescent nanoclusters, which can serve as an effective fluorescent probe. Here, we report a method for the synthesis of copper nanoclusters (Cu NCs) using tripeptides as templates, which also act as stabilizers and reducing agents. The synthesis conditions and properties were explored and optimized. Under optimal conditions, the Cu NCs exhibit excellent stability and are strongly fluorescent. The Cu NCs can detect 0.1–1.0 μmol/L of ascorbic acid with a low detection limit of 0.075 μmol/L, demonstrating high sensitivity and offering significant application potential for the trace of ascorbic acid in various substances. It also provides new ideas for the assembly of metal nanoclusters and the construction of fluorescent probe sensing platforms. Full article
(This article belongs to the Special Issue Nanomaterial-Based Biochemical Sensors and Their Applications)
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14 pages, 5187 KiB  
Article
Improving Triethylamine-Sensing Performance of WO3 Nanoplates through In Situ Heterojunction Construction
by Kuan Tian, Kai Yang, Xuening Ren, Yuxin Miao, Mengyao Liu, Mingxing Su, Jiawen Wu, Yu’an Sun and Pengcheng Xu
Sensors 2024, 24(17), 5606; https://doi.org/10.3390/s24175606 - 29 Aug 2024
Cited by 2 | Viewed by 3783
Abstract
Surface engineering techniques can be used to develop high-performance gas sensing materials and advance the development of sensors. In this study, we improved the gas sensing performance of two-dimensional (2D) WO3 nanoplates by combining surface Zn modification and the in situ formation [...] Read more.
Surface engineering techniques can be used to develop high-performance gas sensing materials and advance the development of sensors. In this study, we improved the gas sensing performance of two-dimensional (2D) WO3 nanoplates by combining surface Zn modification and the in situ formation of ZnWO4/WO3 heterojunctions. Introducing Zn atoms by surface modification can reconstruct the atomic surface of 2D WO3 nanoplates, creating additional active sites. This allowed for the preparation of various types of ZnWO4/WO3 heterojunctions on the surface of the WO3 nanoplates, which improved the selectivity and sensitivity to the target gas triethylamine. The sensor exhibited good gas sensing performance for triethylamine even at low operating temperatures and strongly resisted humidity changes. The ZnWO4/WO3 material we prepared demonstrated a nearly threefold improvement in the triethylamine (TEA) response, with a gas sensing responsivity of 40.75 for 10 ppm of TEA at 250 °C. The sensor based on ZnWO4/WO3 has a limit of detection (LOD) for TEA of 200 ppb in practical measurements (its theoretical LOD is even as low as 31 ppb). The method of growing ZnWO4 on the surface of WO3 nanoplates using surface modification techniques to form surface heterojunctions differs from ordinary composites. The results suggest that the in situ construction of surface heterojunctions using surface engineering strategies, such as in situ modifying, is a practical approach to enhance the gas sensing properties and resistance to the humidity changes of metal oxide materials. Full article
(This article belongs to the Special Issue Nanomaterial-Based Biochemical Sensors and Their Applications)
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