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Electrochemical Nanobiosensors II

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1175

Special Issue Editor


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Guest Editor
Nanobioanalysis Group, Department of Physical and Analytical Chemistry, University of Oviedo, Oviedo, Spain
Interests: nanobiosensors; lateral flow analysis; electrochemical biosensors; electrocatalysis; nanochannels
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Special Issue Information

Dear Colleagues,

Investigations on nanomaterials have increased rapidly in recent years due to their size and shape-dependent physical, chemical and electrochemical properties, which make them extremely useful in sensing and biosensing applications. The size and the composition of nanostructured materials are advantageous over the corresponding bulk structure because a target binding event (i.e., DNA hybridization, immunoreaction or aptamer recognition) involving nanomaterials can have a significant effect on its electrochemical properties (revealed through voltammetric, potentiometric, conductometric or impedimetric measurements), offering novel options for bioanalysis.

The aim of this Special Issue is to focus on the most recent strategies and developments in this field. Papers should address the use of innovative nanomaterials and/or the study and application of novel electrical/electrochemical properties and/or signal amplification capabilities of such materials in the development of biosensors. Metallic/semiconductor nanoparticles, nanoporous platforms and 2D materials are among the cutting-edge nanomaterials expected to be explored in this Special Issue.

Both review articles and original research papers are welcome.

Dr. Alfredo de la Escosura-Muñiz
Guest Editor

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Keywords

  • biosensors
  • electroanalysis
  • nanomaterial
  • nanoparticle
  • nanopore/nanochannel
  • 2D material

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Published Papers (1 paper)

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Research

11 pages, 2476 KiB  
Communication
An Insulin-Modified pH-Responsive Nanopipette Based on Ion Current Rectification
by Xu-Fan Wang, Yi-Fan Duan, Yue-Qian Zhu, Zi-Jing Liu, Yu-Chen Wu, Tian-Hao Liu, Ling Zhang, Jian-Feng Wei and Guo-Chang Liu
Sensors 2024, 24(13), 4264; https://doi.org/10.3390/s24134264 - 30 Jun 2024
Viewed by 695
Abstract
The properties of nanopipettes largely rely on the materials introduced onto their inner walls, which allow for a vast extension of their sensing capabilities. The challenge of simultaneously enhancing the sensitivity and selectivity of nanopipettes for pH sensing remains, hindering their practical applications. [...] Read more.
The properties of nanopipettes largely rely on the materials introduced onto their inner walls, which allow for a vast extension of their sensing capabilities. The challenge of simultaneously enhancing the sensitivity and selectivity of nanopipettes for pH sensing remains, hindering their practical applications. Herein, we report insulin-modified nanopipettes with excellent pH response performances, which were prepared by introducing insulin onto their inner walls via a two-step reaction involving silanization and amidation. The pH response intensity based on ion current rectification was significantly enhanced by approximately 4.29 times when utilizing insulin-modified nanopipettes compared with bare ones, demonstrating a linear response within the pH range of 2.50 to 7.80. In addition, insulin-modified nanopipettes featured good reversibility and selectivity. The modification processes were monitored using the I-V curves, and the relevant mechanisms were discussed. The effects of solution pH and insulin concentration on the modification results were investigated to achieve optimal insulin introduction. This study showed that the pH response behavior of nanopipettes can be greatly improved by introducing versatile molecules onto the inner walls, thereby contributing to the development and utilization of pH-responsive nanopipettes. Full article
(This article belongs to the Special Issue Electrochemical Nanobiosensors II)
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